BS8314
antibody from Bioworld Technology, Inc
Targeting: INTS6
DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS8314 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- INTS6 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human INTS6.
- Description
- DICE1 (Deleted in Cancer 1) is a protein mapping to chromosome 13q14, which appears to be a tumor suppressor gene in non-small cell lung carcinoma. Expression of DICE1 is lost or downregulated in most non-small lung carcinomas compared to normal lung tissue. This is most likely due to a loss of heterozygosity (LOH) of chromosome 13, which is prone to deletions and rearrangements in human lung cancers. The DICE1 gene is extremely homologous to the mouse protein, DBI-1, at the carboxy terminus. DBI-1, when expressed at high levels, interferes with the mitogenic response to IGF-1. Both DICE1 and DBI-1 contain the highly conserved DEAD-box motif, which suggests that these proteins are involved in critical aspects of cellular function and regulation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of INTS6 polyclonal antibody