BS8314

antibody from Bioworld Technology, Inc
Targeting: INTS6 DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2
Provider product page for BS8314
Western blot
Immunohistochemistry

Antibody data

Product number
BS8314 - Provider product page
Provider
Bioworld Technology, Inc
Product name
INTS6 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human INTS6.
Description
DICE1 (Deleted in Cancer 1) is a protein mapping to chromosome 13q14, which appears to be a tumor suppressor gene in non-small cell lung carcinoma. Expression of DICE1 is lost or downregulated in most non-small lung carcinomas compared to normal lung tissue. This is most likely due to a loss of heterozygosity (LOH) of chromosome 13, which is prone to deletions and rearrangements in human lung cancers. The DICE1 gene is extremely homologous to the mouse protein, DBI-1, at the carboxy terminus. DBI-1, when expressed at high levels, interferes with the mitogenic response to IGF-1. Both DICE1 and DBI-1 contain the highly conserved DEAD-box motif, which suggests that these proteins are involved in critical aspects of cellular function and regulation.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
INTS6 protein structure - BS8314 shown in red.