INTS6

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. The protein encoded by this gene is a DEAD box protein that is part of a complex that interacts with the C-terminus of RNA polymerase II and is involved in 3' end processing of snRNAs. In addition, this gene is a candidate tumor suppressor and located in the critical region of loss of heterozygosity (LOH). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

integrator complex subunit 6

Protein family

Mapped to UniProt SWISS-PROT, Predicted intracellular proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

13:q14.3 (51354077 - 51454264)

Ensembl ID

ENSG00000102786  (ver. 84.38)

Orthologs

Mouse Ints6: ENSMUSG00000035161

UniProt

Q9UL03

neXtProt

NX_Q9UL03

Human splice variants
Mouse splice variants