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antibody from antibodies-online
Targeting: INTS6
DBI-1, DDX26, DDX26A, DICE1, HDB, INT6, Notchl2
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
- Immunohistochemistry [1]
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- Product number
- ABIN395973 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Integrator Complex Subunit 6 (INTS6) (AA 779-888) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 779-888
- Isotype
- IgG
- Antibody clone number
- 3D9
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Toward a confocal subcellular atlas of the human proteome.
Human INT6 interacts with MCM7 and regulates its stability during S phase of the cell cycle.
Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer.
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions.
Barbe L, Lundberg E, Oksvold P, Stenius A, Lewin E, Björling E, Asplund A, Pontén F, Brismar H, Uhlén M, Andersson-Svahn H
Molecular & cellular proteomics : MCP 2008 Mar;7(3):499-508
Molecular & cellular proteomics : MCP 2008 Mar;7(3):499-508
Human INT6 interacts with MCM7 and regulates its stability during S phase of the cell cycle.
Buchsbaum S, Morris C, Bochard V, Jalinot P
Oncogene 2007 Aug 2;26(35):5132-44
Oncogene 2007 Aug 2;26(35):5132-44
Promoter CpG hypermethylation and downregulation of DICE1 expression in prostate cancer.
Röpke A, Buhtz P, Böhm M, Seger J, Wieland I, Allhoff EP, Wieacker PF
Oncogene 2005 Oct 6;24(44):6667-75
Oncogene 2005 Oct 6;24(44):6667-75
Integrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase II.
Baillat D, Hakimi MA, Näär AM, Shilatifard A, Cooch N, Shiekhattar R
Cell 2005 Oct 21;123(2):265-76
Cell 2005 Oct 21;123(2):265-76
Absence of mutations in DICE1/DDX26 gene in human cancer cell lines with frequent 13q14 deletions.
Hernández M, Papadopoulos N, Almeida TA
Cancer genetics and cytogenetics 2005 Nov;163(1):91-2
Cancer genetics and cytogenetics 2005 Nov;163(1):91-2
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- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
