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LearnGTX70264
antibody from GeneTex
Targeting: RBBP8
COM1, CtIP, RIM, SCKL2
Western blot
Immunocytochemistry Immunoprecipitation Proximity ligation assay Chromatin ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunocytochemistry [2]
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- Product number
- GTX70264 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX70264, RRID:AB_369822
- Product name
- CtIP antibody [19E8]
- Antibody type
- Monoclonal
- Reactivity
- Human, Mouse
- Host
- Mouse
Submitted references Hepatoma-derived growth factor-related protein 2 promotes DNA repair by homologous recombination.
A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint.
CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer.
CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression.
Baude A, Aaes TL, Zhai B, Al-Nakouzi N, Oo HZ, Daugaard M, Rohde M, Jäättelä M
Nucleic acids research 2016 Mar 18;44(5):2214-26
Nucleic acids research 2016 Mar 18;44(5):2214-26
A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
Ahrabi S, Sarkar S, Pfister SX, Pirovano G, Higgins GS, Porter AC, Humphrey TC
Nucleic acids research 2016 Jul 8;44(12):5743-57
Nucleic acids research 2016 Jul 8;44(12):5743-57
RB·E2F1 complex mediates DNA damage responses through transcriptional regulation of ZBRK1.
Liao CC, Tsai CY, Chang WC, Lee WH, Wang JM
The Journal of biological chemistry 2010 Oct 22;285(43):33134-43
The Journal of biological chemistry 2010 Oct 22;285(43):33134-43
Expression of PCNA-binding domain of CtIP, a motif required for CtIP localization at DNA replication foci, causes DNA damage and activation of DNA damage checkpoint.
Gu B, Chen PL
Cell cycle (Georgetown, Tex.) 2009 May 1;8(9):1409-20
Cell cycle (Georgetown, Tex.) 2009 May 1;8(9):1409-20
CtIP silencing as a novel mechanism of tamoxifen resistance in breast cancer.
Wu M, Soler DR, Abba MC, Nunez MI, Baer R, Hatzis C, Llombart-Cussac A, Llombart-Bosch A, Aldaz CM
Molecular cancer research : MCR 2007 Dec;5(12):1285-95
Molecular cancer research : MCR 2007 Dec;5(12):1285-95
CtIP activates its own and cyclin D1 promoters via the E2F/RB pathway during G1/S progression.
Liu F, Lee WH
Molecular and cellular biology 2006 Apr;26(8):3124-34
Molecular and cellular biology 2006 Apr;26(8):3124-34
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using CtIP(GTX70264) antibody at 1:100 dilution.
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- CtIP antibody [19E8] detects CtIP protein at nucleus by immunofluorescent analysis.Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: CtIP protein stained by CtIP antibody [19E8] (GTX70264) diluted at 1:100.Red: Phalloidin, a cytoskeleton marker, diluted at 1:100.
