Explore
Validate
LearnTissue expression
Cell line expression
RBBP8
gene productCOM1, CtIP, RIM, SCKL2
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008]
Featured antibodies
 GeneTex |
 GTX70264 |
6 references | Monoclonal |
WB
ICC 
IP
PLA
ChIP
|
Antibodies
Filters
Enhanced validation Supportive data in Antibodypedia Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider