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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Western blot [1]
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- Product number
- MAB5528 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#MAB5528, RRID:AB_10629687
- Product name
- LCK monoclonal antibody, clone 8E5F9, 4B2C7
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal antibody raised against partial recombinant LCK.
- Isotype
- IgG
- Antibody clone number
- 8E5F9, 4B2C7
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references A constitutively active Lck kinase promotes cell proliferation and resistance to apoptosis through signal transducer and activator of transcription 5b activation.
A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection.
The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.
Shi M, Cooper JC, Yu CL
Molecular cancer research : MCR 2006 Jan;4(1):39-45
Molecular cancer research : MCR 2006 Jan;4(1):39-45
A-770041, a novel and selective small-molecule inhibitor of Lck, prevents heart allograft rejection.
Stachlewitz RF, Hart MA, Bettencourt B, Kebede T, Schwartz A, Ratnofsky SE, Calderwood DJ, Waegell WO, Hirst GC
The Journal of pharmacology and experimental therapeutics 2005 Oct;315(1):36-41
The Journal of pharmacology and experimental therapeutics 2005 Oct;315(1):36-41
The Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.
Hawash IY, Kesavan KP, Magee AI, Geahlen RL, Harrison ML
The Journal of biological chemistry 2002 Feb 15;277(7):5683-91
The Journal of biological chemistry 2002 Feb 15;277(7):5683-91
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis using LCK monoclonal antibody, clone 8E5F9, 4B2C7 (Cat # MAB5528) against truncated LCK recombinant protein (Lane 1) and Jurkat cell lysate (Lane 2).
