LCK

gene product
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
1219 antibodies from 41 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Invitrogen Antibodies
22 antibodies
Biorbyt
50 antibodies
NSJ Bioreagents
6 antibodies
OriGene
28 antibodies
Abgent
14 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
17 antibodies
Novus Biologicals
90 antibodies
Acris Antibodies GmbH
23 antibodies
Boster Biological Technology
3 antibodies
antibodies-online
329 antibodies
Aviva Systems Biology
13 antibodies
GeneTex
21 antibodies
Abnova Corporation
25 antibodies
LifeSpan BioSciences, Inc.
215 antibodies