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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Product number
- ABIN967742 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Lymphocyte-Specific Protein tyrosine Kinase (LCK) (AA 1-191) antibody
- Antibody type
- Monoclonal
- Antigen
- Human Lck
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 28
- Vial size
- 50 µg
- Concentration
- 250 µg/ml
- Storage
- Store undiluted at -20° C.
Submitted references LAT displacement from lipid rafts as a molecular mechanism for the inhibition of T cell signaling by polyunsaturated fatty acids.
Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.
Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions.
A kinase-independent function of Lck in potentiating antigen-specific T cell activation.
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck.
Zeyda M, Staffler G, Horejsi V, Waldhausl W, Stulnig TM
The Journal of biological chemistry 2002 Aug 9;277(32):28418-23
The Journal of biological chemistry 2002 Aug 9;277(32):28418-23
Hierarchy of protein tyrosine kinases in interleukin-2 (IL-2) signaling: activation of syk depends on Jak3; however, neither Syk nor Lck is required for IL-2-mediated STAT activation.
Zhou YJ, Magnuson KS, Cheng TP, Gadina M, Frucht DM, Galon J, Candotti F, Geahlen RL, Changelian PS, O'Shea JJ
Molecular and cellular biology 2000 Jun;20(12):4371-80
Molecular and cellular biology 2000 Jun;20(12):4371-80
Differential loss of T cell signaling molecules in metastatic melanoma patients' T lymphocyte subsets expressing distinct TCR variable regions.
Maccalli C, Pisarra P, Vegetti C, Sensi M, Parmiani G, Anichini A
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 15;163(12):6912-23
Journal of immunology (Baltimore, Md. : 1950) 1999 Dec 15;163(12):6912-23
A kinase-independent function of Lck in potentiating antigen-specific T cell activation.
Xu H, Littman DR
Cell 1993 Aug 27;74(4):633-43
Cell 1993 Aug 27;74(4):633-43
T-lymphocyte interleukin 2-dependent tyrosine protein kinase signal transduction involves the activation of p56lck.
Horak ID, Gress RE, Lucas PJ, Horak EM, Waldmann TA, Bolen JB
Proceedings of the National Academy of Sciences of the United States of America 1991 Mar 1;88(5):1996-2000
Proceedings of the National Academy of Sciences of the United States of America 1991 Mar 1;88(5):1996-2000
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