ADH1C

This gene encodes class I alcohol dehydrogenase, gamma subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class I alcohol dehydrogenase, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. [provided by RefSeq, Jul 2008]

Description

alcohol dehydrogenase 1C (class I), gamma polypeptide

Protein family

Enzymes, FDA approved drug targets, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Kim et al 2014)

Chromosome

4:q23 (99336492 - 99353027)

Ensembl ID

ENSG00000248144  (ver. 84.38)

Orthologs

-

UniProt

P00326

neXtProt

NX_P00326

Human splice variants