NBP2-44861-0.1mg

antibody from Novus Biologicals
Targeting: PTPRC CD45, GP180, LCA, T200
Provider product page for NBP2-44861-0.1mg

Antibody data

Product number
NBP2-44861-0.1mg - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal CD45RA Antibody
Antibody type
Monoclonal
Description
Protein A or G purified. Recognizes a protein of 205kDa-220kDa, identified as CD45RA (Workshop III). CD45RA is isoforms of the human leukocyte common antigen (CD45). Human CD45 contains three exons which encode peptide segments designated A, B and C, respectively. The differential splicing of the exons generates at least five isoforms, ABC, AB, BC, B and O. This antibody reacts with ABC and BC isoforms. CD45RA is expressed on 40-50% of peripheral CD4+ T-cells, 50% of peripheral CD8+ T-cells, B-cells, and leukemic B-cell lines. T-cells expressing CD45RA are naive or virgin T-cells. T-cells expressing CD45RO are memory T-cells. CD45RA and CD45RO define complementary, predominantly non-overlapping populations of resting peripheral T-cells. This MAb is useful in study on the subpopulation of CD4+ or CD8+ T-cells. It can especially be used to differentiate T-cell lymphomas (CD45RO +ve) from B cell lymphomas (CD45RA +ve).
Reactivity
Human
Host
Mouse
Isotype
IgG
Vial size
0.1 mg
Concentration
0.2 mg/ml
Storage
Store at 4C.
PTPRC protein structure - NBP2-44861-0.1mg shown in red.