Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
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- Product number
- NBP2-32937-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CD45RB Antibody
- Antibody type
- Monoclonal
- Description
- Protein A purified. CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CD45RB Antibody (PD7/26) [NBP2-32937] - Western Blot Analysis of human Spleen tissue lysates using CD45RB Antibody (PD7/26).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD45RB Antibody (PD7/26) [NBP2-32937] - Formalin-fixed, paraffin-embedded human tonsil (10X) stained with CD45RB MAb (PD7/26).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD45RB Antibody (PD7/26) [NBP2-32937] - Formalin-fixed, paraffin-embedded human tonsil (20X) stained with CD45RB MAb (PD7/26).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: CD45RB Antibody (PD7/26) [NBP2-32937] - Flow Cytometric Analysis of PFA-fixed Raji cells using CD45RB Antibody (PD7/26) followed by Goat anti-Mouse IgG-CF488 (Blue); Isotype control (Red).