Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [2]
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Validation data
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- Product number
- NBP2-47958-0.1mg - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal CD45RB Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. CD45R, also designated CD45 and PTPRC, is identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45RB is expressed on mature B-lymphocytes and the majority of lymphomas and leukemias of B-cell origin.
- Reactivity
- Human, Rat, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CD45RB Antibody (PTPRC/1132) - Azide and BSA Free [NBP2-47958] - Human Spleen tissue lysates using CD45RB Monoclonal Antibody (PTPRC/1132).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CD45RB Antibody (PTPRC/1132) - Azide and BSA Free [NBP2-47958] - Daudi cell lysate using CD45RB Monoclonal Antibody (PTPRC/1132).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD45RB Antibody (PTPRC/1132) - Azide and BSA Free [NBP2-47958] - Human Lymphoma stained with CD45RB Monoclonal Antibody (PTPRC/1132).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: CD45RB Antibody (PTPRC/1132) - Azide and BSA Free [NBP2-47958] - Human Tonsil stained with CD45RB Monoclonal Antibody (PTPRC/1132).