Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Other assay [1]
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- Product number
- MHCD4506 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD45 Monoclonal Antibody (HI30), TRI-COLOR™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- The TRI-COLOR® conjugate is a tandem R-phycoerythrin (PE)-Cy5® conjugate that permits simultaneous multicolor labeling and detection of multiple targets with excitation by a single excitation source-the 488 nm line of the argon-ion laser.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- HI30
- Vial size
- 500 µL
- Storage
- 4° C, store in dark
Submitted references Tumor-endogenous PD-1 promotes cell proliferation and predicts poor survival in non-small cell lung cancer.
Synovial IL-21/TNF-producing CD4(+) T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes.
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection.
Methylation Analysis in Distinct Immune Cell Subsets in Type 1 Diabetes.
Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection.
High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.
Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system.
The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration.
A new protocol for multiple inhalation of IFN-gamma successfully treats MDR-TB: a case study.
Gan F, Zhang C, Xia L, Deng S
Translational cancer research 2022 Jan;11(1):3-13
Translational cancer research 2022 Jan;11(1):3-13
Synovial IL-21/TNF-producing CD4(+) T cells induce joint destruction in rheumatoid arthritis by inducing matrix metalloproteinase production by fibroblast-like synoviocytes.
Lebre MC, Vieira PL, Tang MW, Aarrass S, Helder B, Newsom-Davis T, Tak PP, Screaton GR
Journal of leukocyte biology 2017 Mar;101(3):775-783
Journal of leukocyte biology 2017 Mar;101(3):775-783
Expression of a Chimeric Antigen Receptor Specific for Donor HLA Class I Enhances the Potency of Human Regulatory T Cells in Preventing Human Skin Transplant Rejection.
Boardman DA, Philippeos C, Fruhwirth GO, Ibrahim MA, Hannen RF, Cooper D, Marelli-Berg FM, Watt FM, Lechler RI, Maher J, Smyth LA, Lombardi G
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2017 Apr;17(4):931-943
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2017 Apr;17(4):931-943
Methylation Analysis in Distinct Immune Cell Subsets in Type 1 Diabetes.
Dang MN, Bradford CM, Pozzilli P, Leslie RD
Methods in molecular biology (Clifton, N.J.) 2016;1433:143-51
Methods in molecular biology (Clifton, N.J.) 2016;1433:143-51
Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection.
Yawata N, Selva KJ, Liu YC, Tan KP, Lee AW, Siak J, Lan W, Vania M, Arundhati A, Tong L, Li J, Mehta JS, Yawata M
Mucosal immunology 2016 Jan;9(1):159-70
Mucosal immunology 2016 Jan;9(1):159-70
High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells.
Kanderova V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, Hrusak O, Lund-Johansen F, Kalina T
Molecular & cellular proteomics : MCP 2016 Apr;15(4):1246-61
Molecular & cellular proteomics : MCP 2016 Apr;15(4):1246-61
Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system.
Yang Y, Li J, Pan X, Zhou P, Yu X, Cao H, Wang Y, Li L
Biotechnology and bioengineering 2013 Mar;110(3):958-68
Biotechnology and bioengineering 2013 Mar;110(3):958-68
The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration.
Kaucká M, Plevová K, Pavlová S, Janovská P, Mishra A, Verner J, Procházková J, Krejcí P, Kotasková J, Ovesná P, Tichy B, Brychtová Y, Doubek M, Kozubík A, Mayer J, Pospísilová S, Bryja V
Cancer research 2013 Mar 1;73(5):1491-501
Cancer research 2013 Mar 1;73(5):1491-501
A new protocol for multiple inhalation of IFN-gamma successfully treats MDR-TB: a case study.
Grahmann PR, Braun RK
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2008 Jun;12(6):636-44
The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2008 Jun;12(6):636-44
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Expression of tumor-endogenous PD-1 in clinical samples. (A) PD-1 expression in fresh lung cancer tissue by flow cytometry; (B) statistical result of PD-1 expression in fresh lung cancer tissue by flow cytometry; (C) tumor-endogenous PD-1 expression in a cohort of 100 patients; (D) PD-1 expression in tumor cells and infiltrating lymphocytes in IHC; (E) tumor-endogenous PD-1 expression classified by pathological N stage; (F,G) Kaplan-Meier curves for OS and DFS of patients with tumor-endogenous PD-1. PD-1, programmed cell death protein 1; IHC, immunohistochemistry; OS, overall survival; DFS, disease-free survival.