Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [2]
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Validation data
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- Product number
- ABIN316599 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
- Antibody type
- Monoclonal
- Antigen
- Protein tyrosine Phosphatase, Receptor Type, C (PTPRC)
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Recombinant human CD45
- Isotype
- IgG
- Vial size
- 50 uL
- Concentration
- 1.0 mg/mL
Submitted references Genomic organization of the channel catfish CD45 functional gene and CD45 pseudogenes.
Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells.
A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.
Kountikov E, Wilson M, Quiniou S, Miller N, Clem W, Bengtén E
Immunogenetics 2005 Jun;57(5):374-83
Immunogenetics 2005 Jun;57(5):374-83
Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells.
Spertini F, Perret-Menoud V, Barbier N, Chatila T, Barbey C, Corthesy B
Immunology 2004 Dec;113(4):441-52
Immunology 2004 Dec;113(4):441-52
A high-frequency polymorphism in exon 6 of the CD45 tyrosine phosphatase gene (PTPRC) resulting in altered isoform expression.
Stanton T, Boxall S, Hirai K, Dawes R, Tonks S, Yasui T, Kanaoka Y, Yuldasheva N, Ishiko O, Bodmer W, Beverley PC, Tchilian EZ
Proceedings of the National Academy of Sciences of the United States of America 2003 May 13;100(10):5997-6002
Proceedings of the National Academy of Sciences of the United States of America 2003 May 13;100(10):5997-6002
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Flow cytometry
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Image(s): Flow cytometry