304029

PTPRC antibody from BioLegend
CD45, GP180, LCA, T200

Antibody data

Product number
304029
Provider
BioLegend
Proper citation
BioLegend Cat#304029, RRID:AB_2174123
Product name
Pacific Blue™ anti-human CD45 [HI30]
Provider product page
BioLegend - 304029
Antibody type
Monoclonal
Antigen
CD45
Description
CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA), B220, and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -