304029

antibody from BioLegend

Targeting: PTPRC CD45, GP180, LCA, T200

Antibody data

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Validation data

Product number: 304029 - Provider product page
Provider: BioLegend
Proper citation: BioLegend Cat#304029, RRID:AB_2174123
Product name: Pacific Blue™ anti-human CD45 [HI30]
Antibody type: Monoclonal
Antigen: CD45
Description: CD45 is a 180-240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA), B220, and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes and platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Reactivity: Human, Simian
Host: Mouse
Conjugate: Blue dye
Isotype: IgG
Vial size: 100 tests
Storage: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

PTPRC protein structure - 304029 shown in red.