304114

PTPRC antibody from BioLegend
CD45, GP180, LCA, T200

Antibody data

Product number
304114
Provider
BioLegend
Proper citation
BioLegend Cat#304114, RRID:AB_528816
Product name
Alexa Fluor® 488 anti-human CD45RA [HI100]
Provider product page
BioLegend - 304114
Antibody type
Monoclonal
Antigen
CD45RA
Description
CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.
Reactivity
Human, Simian
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
100 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -