RA0619

antibody from Oursmab
Targeting: PTPRC CD45, GP180, LCA, T200
Provider product page for RA0619
Western blot
ELISA
Immunocytochemistry
Flow cytometry
Functional assay

Antibody data

Product number
RA0619 - Provider product page
Provider
Oursmab
Product name
Apamistamab (Biosimilar Reference Antibody) (PTPRC)
Antibody type
Monoclonal
Description
Apamistamab is a murine monoclonal antibody that targets CD45, a pan-leukocyte antigen. Its therapeutic application is as a radioimmunoconjugate, specifically Iodine-131 labeled Apamistamab (131I-Apamistamab, developed as Iomab-B). It is designed for conditioning therapy prior to hematopoietic stem cell transplantation in patients with relapsed or refractory acute myeloid leukemia and other hematologic malignancies. The antibody delivers a targeted, high dose of radiation directly to CD45-expressing bone marrow and leukemia cells, thereby ablating the diseased marrow to create space for donor stem cell engraftment, while aiming to spare non-hematopoietic tissues.
Reactivity
Human
Isotype
IgG
Vial size
100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
PTPRC protein structure - RA0619 shown in red.