ABIN966098

antibody from antibodies-online

Targeting: ESR1 ER-alpha, Era, ESR, NR3A1

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN966098

Provider

antibodies-online

Product name

anti-Estrogen Receptor 1 (ESR1) (pSer104) antibody

Antibody type

Polyclonal

Antigen

The antiserum was produced against synthesized phosphopeptide derived from human Estrogen Receptor- around the phosphorylation site of serine 104 (S-V-SP-P-S).

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

Reactivity

Human, Mouse

Host

Rabbit

Epitope

pSer104

Vial size

100 μg

Concentration

100ug/100ul.

Storage

-20°C

References

Submitted references

Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity.

Medunjanin S, Hermani A, De Servi B, Grisouard J, Rincke G, Mayer D
The Journal of biological chemistry 2005 Sep 23;280(38):33006-14

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Potentiation of human estrogen receptor alpha transcriptional activation through phosphorylation of serines 104 and 106 by the cyclin A-CDK2 complex.

Rogatsky I, Trowbridge JM, Garabedian MJ
The Journal of biological chemistry 1999 Aug 6;274(32):22296-302