Tissue expression
Cell line expression

ESR1

gene product
ER-alpha, Era, ESR, NR3A1 
This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020]
More gene data

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4121 antibodies from 54 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
GeneTex
46 antibodies
Atlas Antibodies
3 antibodies
Invitrogen Antibodies
55 antibodies
NSJ Bioreagents
36 antibodies
antibodies-online
1483 antibodies
Novus Biologicals
248 antibodies
R&D Systems
7 antibodies
Enzo Life Sciences
6 antibodies
Boster Biological Technology
17 antibodies
OriGene
125 antibodies
NovoPro Bioscience Inc.
20 antibodies
Biorbyt
214 antibodies
Abnova Corporation
50 antibodies
LifeSpan BioSciences, Inc.
596 antibodies
Acris Antibodies GmbH
86 antibodies
Cusabio Biotech Co., Ltd
37 antibodies
Aviva Systems Biology
41 antibodies
Affinity Biosciences
11 antibodies
Signalway Antibody LLC
8 antibodies
Abgent
33 antibodies
Cell Signaling Technology, Inc
9 antibodies
HUABIO Research
4 antibodies
Bethyl Laboratories
5 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
Proteintech Group
1 antibody
Bioworld Technology, Inc
11 antibodies
St John's Laboratory
29 antibodies
ProSci
16 antibodies
Wuhan Fine Biotech Co., Ltd.
1 antibody
Creative Biolabs
115 antibodies
Spring Bioscience
8 antibodies
Abbkine Scientific Co.Ltd.
14 antibodies
FabGennix
9 antibodies
Creative Diagnostics
32 antibodies
RabMAbs
14 antibodies
Exalpha Biologicals, Inc.
2 antibodies
MyBioSource
52 antibodies
MilliporeSigma / Merck KGaA
25 antibodies
Abbexa
83 antibodies
Abbiotec
10 antibodies
EMD Millipore
13 antibodies
ABEOMICS Inc.
2 antibodies
Leading Biology
32 antibodies
Active Motif
1 antibody
United States Biological
344 antibodies
GenWay
30 antibodies
RayBiotech, Inc.
9 antibodies
Abiocode, Inc.
1 antibody
DB Biotech
1 antibody
MS Validated Antibodies GmbH
1 antibody
BioLegend (formerly Covance Antibody Products)
1 antibody
Aalto Bio Reagents Ltd.
1 antibody