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- Antibody Data
- Antigen structure
- References [118]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 21244-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#21244-1-AP, RRID:AB_11042600
- Product name
- ER antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ER antibody (Cat. #21244-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Cholecystokinin-mediated effect of insulin pathway on the steroidogenic activity of follicular granulosa cells in Camelus bactrianus: In vitro study.
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Cardamomin Inhibits the Proliferation and Tumorigenesis of Bladder Cancer by ESR1 in PI3K/AKT Pathway.
Exploring the inhibitory impact of Mongolian medicinal He-Zi-3 soup on mammary gland hyperplasia in rats induced by estrogen and progestogen.
Establishment of patient-derived organoids for guiding personalized therapies in breast cancer patients.
New mode of action of curcumin on prostate cancer cells: Modulation of endoplasmic reticulum-associated degradation mechanism and estrogenic signaling.
Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Ge-gen decoction alleviates primary dysmenorrhoea symptoms in a rat model.
Integrating Network Pharmacology and Bioinformatics to Explore the Effects of Dangshen (Codonopsis pilosula) Against Hepatocellular Carcinoma: Validation Based on the Active Compound Luteolin.
Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathway.
Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro.
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Estrogen Receptor-α Exacerbates EGF-Inducing Airway Remodeling and Mucus Production in Bronchial Epithelium of Asthmatics.
A patient-derived organoid-based study identified an ASO targeting SNORD14E for endometrial cancer through reducing aberrant FOXM1 Expression and β-catenin nuclear accumulation.
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Immune characteristics analysis and construction of a four-gene prognostic signature for lung adenocarcinoma based on estrogen reactivity.
Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis.
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Variation in IL6ST cytokine family function and the potential of IL6 trans-signalling in ERα positive breast cancer cells.
A NOTCH1 Mutation Found in a Newly Established Ovarian Cancer Cell Line (FDOVL) Promotes Lymph Node Metastasis in Ovarian Cancer.
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII.
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Betulinic acid alleviates zearalenone-induced uterine injury in mice.
FABP4 mediates endoplasmic reticulum stress and autophagy to regulate endometrial epithelial cell function during early sheep gestation.
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells.
Bidirectional crosstalk of the cAMP/ROS-dependent signaling pathways in inflammatory macrophage: An activation of formononetin.
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.
Hybrid Broussonetia papyrifera Fermented Feed Can Play a Role Through Flavonoid Extracts to Increase Milk Production and Milk Fatty Acid Synthesis in Dairy Goats.
Development of a Multi-target Protein Biomarker Assay for Circulating Tumor Cells.
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Exploring the impact of ovariectomy on hair growth: can ovariectomized mouse serve as a model for investigating female pattern hair loss in humans?
Oral exposure to DEHP may stimulate prostatic hyperplasia associated with upregulation of COX-2 and L-PGDS expressions in male adult rats.
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
Preimplantation triclosan exposure alters uterine receptivity through affecting tight junction protein†.
Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Genistein reverses the effect of 17β-estradiol on exacerbating experimental occlusal interference-induced chronic masseter hyperalgesia in ovariectomised rats.
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Maternal Perinatal Exposure to Dibutyl Phthalate Promotes Ovarian Dysfunction in Adult Female Offspring via Downregulation of TGF-β2 and TGF-β3.
Discovery of Thieno[2,3-e]indazole Derivatives as Novel Oral Selective Estrogen Receptor Degraders with Highly Improved Antitumor Effect and Favorable Druggability.
Exploration of the Danggui Buxue Decoction Mechanism Regulating the Balance of ESR and AR in the TP53-AKT Signaling Pathway in the Prevention and Treatment of POF.
Pan-Cancer Prognostic Role and Targeting Potential of the Estrogen-Progesterone Axis.
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Weighted gene coexpression network analysis reveals ESR1, FLNA and Furin as hub genes for DEHP-induced prepubertal testicular injury.
The "Matrisome" reveals the characterization of skin keloid microenvironment.
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease.
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
InvivoPen: A novel plasma source for in vivo cancer treatment.
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Neuroprotective effects of vitamin D and 17ß-estradiol against ovariectomy-induced neuroinflammation and depressive-like state: Role of the AMPK/NF-κB pathway.
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Effect of liquiritin on neuroendocrine-immune network in menopausal rat model.
Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression.
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Targeting claudin-4 enhances chemosensitivity in breast cancer.
The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats.
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome.
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Vaccarin promotes proliferation of and milk synthesis in bovine mammary epithelial cells through the Prl receptor-PI3K signaling pathway.
The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A.
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
TP53 Mutations Promote Immunogenic Activity in Breast Cancer.
Dual targeting of estrogen receptor α and estrogen-related receptor α: a novel endocrine therapy for endometrial cancer.
Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity.
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.
Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats.
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ(1-42) -induced reactive oxygen species/reactive nitrogen species generation.
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines.
Rutin attenuates cerebral ischemia-reperfusion injury in ovariectomized rats via estrogen-receptor-mediated BDNF-TrkB and NGF-TrkA signaling.
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring.
Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity.
Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats.
EZH2 inhibition sensitizes tamoxifen‑resistant breast cancer cells through cell cycle regulation.
17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.
HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma‑not otherwise specified.
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3.
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor.
Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia.
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle.
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.
MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention.
Guo L, Zhang Y
Reproduction in domestic animals = Zuchthygiene 2024 May;59(5):e14586
Reproduction in domestic animals = Zuchthygiene 2024 May;59(5):e14586
Polyphyllin B inhibited STAT3/NCOA4 pathway and restored gut microbiota to ameliorate lung tissue injury in cigarette smoke-induced mice.
Wang Q, He Z, Zhu J, Hu M, Yang L, Yang H
BMC biotechnology 2024 Mar 8;24(1):13
BMC biotechnology 2024 Mar 8;24(1):13
Cardamomin Inhibits the Proliferation and Tumorigenesis of Bladder Cancer by ESR1 in PI3K/AKT Pathway.
Zhang P, Song D, Fang Z, Sun D, Wang L, Shi L, Gao L, Jiang X
Biochemical genetics 2024 Jun 12;
Biochemical genetics 2024 Jun 12;
Exploring the inhibitory impact of Mongolian medicinal He-Zi-3 soup on mammary gland hyperplasia in rats induced by estrogen and progestogen.
Liang C, Mu X, Bao Q, Borzigin P, Sheng H, Han X, Chen Y, Wang T
Journal of ethnopharmacology 2024 Jul 15;329:117854
Journal of ethnopharmacology 2024 Jul 15;329:117854
Establishment of patient-derived organoids for guiding personalized therapies in breast cancer patients.
Wu H, Wang W, Zhang Y, Chen Y, Shan C, Li J, Jia Y, Li C, Du C, Cai Y, Zhang Y, Zhang S, Wu F
International journal of cancer 2024 Jul 15;155(2):324-338
International journal of cancer 2024 Jul 15;155(2):324-338
New mode of action of curcumin on prostate cancer cells: Modulation of endoplasmic reticulum-associated degradation mechanism and estrogenic signaling.
Erzurumlu Y, Dogan HK, Catakli D
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23636
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23636
Effects of BXSMD on ESR1 and ESR2 expression in CSD female mice.
Wang S, Liu L, Liang S, Yang J, Zhang Y, Liu X
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116973
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):116973
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Wang Z, Cui F, Chen Y, Liu H, Zhang Y, Shi Y, Zhang Y, Wang Y, Liang N, Xu L, Liu Y, Liu Z, Shi W
Tissue & cell 2024 Feb;86:102284
Tissue & cell 2024 Feb;86:102284
Ge-gen decoction alleviates primary dysmenorrhoea symptoms in a rat model.
Xie Y, Xu H, Gu Z
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2337691
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 2024 Dec;44(1):2337691
Integrating Network Pharmacology and Bioinformatics to Explore the Effects of Dangshen (Codonopsis pilosula) Against Hepatocellular Carcinoma: Validation Based on the Active Compound Luteolin.
Yu Y, Ding S, Xu X, Yan D, Fan Y, Ruan B, Zhang X, Zheng L, Jie W, Zheng S
Drug design, development and therapy 2023;17:659-673
Drug design, development and therapy 2023;17:659-673
Fibroblast growth factor 1 ameliorates thin endometrium in rats through activation of the autophagic pathway.
Zhu J, Li Z, Yin F, Yu X, Lu Y, Zhou T, Gong F, Xu Z
Frontiers in pharmacology 2023;14:1143096
Frontiers in pharmacology 2023;14:1143096
Effects of 7-ketocholesterol on tamoxifen efficacy in breast carcinoma cell line models in vitro.
Spalenkova A, Ehrlichova M, Wei S, Peter Guengerich F, Soucek P
The Journal of steroid biochemistry and molecular biology 2023 Sep;232:106354
The Journal of steroid biochemistry and molecular biology 2023 Sep;232:106354
Estrogens drive the endoplasmic reticulum-associated degradation and promote proto-oncogene c-Myc expression in prostate cancer cells by androgen receptor/estrogen receptor signaling.
Erzurumlu Y, Dogan HK, Catakli D, Aydogdu E, Muhammed MT
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Journal of cell communication and signaling 2023 Sep;17(3):793-811
Estrogen Receptor-α Exacerbates EGF-Inducing Airway Remodeling and Mucus Production in Bronchial Epithelium of Asthmatics.
Qin L, Yue J, Guo M, Zhang C, Fang X, Zhang S, Bai W, Liu X, Xie M
Allergy, asthma & immunology research 2023 Sep;15(5):614-635
Allergy, asthma & immunology research 2023 Sep;15(5):614-635
A patient-derived organoid-based study identified an ASO targeting SNORD14E for endometrial cancer through reducing aberrant FOXM1 Expression and β-catenin nuclear accumulation.
Chen X, Liu X, Li QH, Lu BF, Xie BM, Ji YM, Zhao Y
Journal of experimental & clinical cancer research : CR 2023 Sep 5;42(1):230
Journal of experimental & clinical cancer research : CR 2023 Sep 5;42(1):230
Effect of Tamoxifen on Proteome Expression during In Vitro Myogenesis in Murine Skeletal Muscle C(2)C(12) Cells.
Morris EA, Abreu A, Scordilis SP
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Journal of proteome research 2023 Sep 1;22(9):3040-3053
Immune characteristics analysis and construction of a four-gene prognostic signature for lung adenocarcinoma based on estrogen reactivity.
Wang Y, Yu T, Chen J, Zhao R, Diao M, Mei P, He S, Qiu W, Ye G, Jiang L, Xiao H, Liao Y
BMC cancer 2023 Oct 31;23(1):1047
BMC cancer 2023 Oct 31;23(1):1047
Endometrial cancer (EC) derived G3BP1 overexpression and mutant promote EC tumorigenesis and metastasis via SPOP/ERα axis.
Ge Y, Jin J, Chen G, Li J, Ye M, Jin X
Cell communication and signaling : CCS 2023 Oct 30;21(1):303
Cell communication and signaling : CCS 2023 Oct 30;21(1):303
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Fu Q, Li T, Zhang C, Ma X, Meng L, Liu L, Shao K, Wu G, Zhu X, Zhao X
Cell communication and signaling : CCS 2023 May 4;21(1):95
Cell communication and signaling : CCS 2023 May 4;21(1):95
Variation in IL6ST cytokine family function and the potential of IL6 trans-signalling in ERα positive breast cancer cells.
Mosly D, MacLeod K, Moir N, Turnbull A, Sims AH, Langdon SP
Cellular signalling 2023 Mar;103:110563
Cellular signalling 2023 Mar;103:110563
A NOTCH1 Mutation Found in a Newly Established Ovarian Cancer Cell Line (FDOVL) Promotes Lymph Node Metastasis in Ovarian Cancer.
Jiang W, Ouyang X, Jiang C, Yin L, Yao Q, Pei X, Ji Z, Li M, Song S, Yang W, Huang S, Yang H, Shan B
International journal of molecular sciences 2023 Mar 7;24(6)
International journal of molecular sciences 2023 Mar 7;24(6)
Low-dose phthalates promote breast cancer stem cell properties via the oncogene ΔNp63α and the Sonic hedgehog pathway.
Cao WS, Zhao MJ, Chen Y, Zhu JY, Xie CF, Li XT, Geng SS, Zhong CY, Fu JY, Wu JS
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
Ecotoxicology and environmental safety 2023 Mar 1;252:114605
CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
Zheng C, Wei Y, Zhang P, Xu L, Zhang Z, Lin K, Hou J, Lv X, Ding Y, Chiu Y, Jain A, Islam N, Malovannaya A, Wu Y, Ding F, Xu H, Sun M, Chen X, Chen Y
The Journal of clinical investigation 2023 Mar 1;133(5)
The Journal of clinical investigation 2023 Mar 1;133(5)
Anti-Postmenopausal osteoporosis effects of Isopsoralen: A bioinformatics-integrated experimental study.
Li H, Wang C, Jin Y, Cai Y, Yao J, Meng Q, Wu J, Wang H, Sun H, Liu M
Phytotherapy research : PTR 2023 Jan;37(1):231-251
Phytotherapy research : PTR 2023 Jan;37(1):231-251
PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII.
Rambout X, Cho H, Blanc R, Lyu Q, Miano JM, Chakkalakal JV, Nelson GM, Yalamanchili HK, Adelman K, Maquat LE
Molecular cell 2023 Jan 19;83(2):186-202.e11
Molecular cell 2023 Jan 19;83(2):186-202.e11
Evaluation of toxicological effects of bisphenol S with an in vitro human bone marrow mesenchymal stem cell: Implications for bone health.
Li M, Li T, Yin J, Xie C, Zhu J
Toxicology 2023 Jan 15;484:153408
Toxicology 2023 Jan 15;484:153408
Bisphenol A and Di(2-Ethylhexyl) Phthalate promote pulmonary carcinoma in female rats via estrogen receptor beta: In vivo and in silico analysis.
Xiao M, Zhang Y, Zhang X, Zhang G, Jin C, Yang J, Wu S, Lu X
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Ecotoxicology and environmental safety 2023 Jan 15;250:114496
Betulinic acid alleviates zearalenone-induced uterine injury in mice.
Yang C, Chen Y, Yang M, Li J, Wu Y, Fan H, Kong X, Ning C, Wang S, Xiao W, Yuan Z, Yi J, Wu J
Environmental pollution (Barking, Essex : 1987) 2023 Jan 1;316(Pt 1):120435
Environmental pollution (Barking, Essex : 1987) 2023 Jan 1;316(Pt 1):120435
FABP4 mediates endoplasmic reticulum stress and autophagy to regulate endometrial epithelial cell function during early sheep gestation.
Song M, Hao K, Qi F, Zhao W, Wang Z, Wang J, Hu G
The Journal of reproduction and development 2023 Dec 8;69(6):298-307
The Journal of reproduction and development 2023 Dec 8;69(6):298-307
Glutathione-responsive PROTAC for targeted degradation of ERα in breast cancer cells.
Zhou Z, Fan H, Yu D, Shi F, Li Q, Zhang Z, Wang X, Zhang X, Dong C, Sun H, Mi W
Bioorganic & medicinal chemistry 2023 Dec 15;96:117526
Bioorganic & medicinal chemistry 2023 Dec 15;96:117526
Bidirectional crosstalk of the cAMP/ROS-dependent signaling pathways in inflammatory macrophage: An activation of formononetin.
Zhang LF, Zhang XY, Wang AC, Feng YJ, Qi XM, Zhang YL, Li QF, Qiao YB, Li QS
Toxicology and applied pharmacology 2023 Aug 1;472:116571
Toxicology and applied pharmacology 2023 Aug 1;472:116571
SERD-NHC-Au(I) complexes for dual targeting ER and TrxR to induce ICD in breast cancer.
Lu Y, Sheng X, Liu C, Liang Z, Wang X, Liu L, Wen Z, Yang Z, Du Q, Liu W
Pharmacological research 2023 Apr;190:106731
Pharmacological research 2023 Apr;190:106731
Knockout of murine Lyplal1 confers sex-specific protection against diet-induced obesity.
Vohnoutka RB, Kuppa A, Hegde Y, Chen Y, Pant A, Tohme ME, Choi EK, McCarty SM, Bagchi DP, Du X, Chen Y, Chen VL, Mori H, Bielak LF, Maguire LH, Handelman SK, Sexton JZ, Saunders TL, Halligan BD, Speliotes EK
Journal of molecular endocrinology 2023 Apr 1;70(3)
Journal of molecular endocrinology 2023 Apr 1;70(3)
Hybrid Broussonetia papyrifera Fermented Feed Can Play a Role Through Flavonoid Extracts to Increase Milk Production and Milk Fatty Acid Synthesis in Dairy Goats.
Zhao M, Lv D, Hu J, He Y, Wang Z, Liu X, Ran B, Hu J
Frontiers in veterinary science 2022;9:794443
Frontiers in veterinary science 2022;9:794443
Development of a Multi-target Protein Biomarker Assay for Circulating Tumor Cells.
Li D, Wang C, Ni Y, Liu Y, Wang W, Zhang S, Chang HC, Senapati S
Methods in molecular biology (Clifton, N.J.) 2022;2394:3-18
Methods in molecular biology (Clifton, N.J.) 2022;2394:3-18
Neuroprotective Mechanism of Icariin on Hypoxic Ischemic Brain Damage in Neonatal Mice.
Wang M, Yang X, Zhou Q, Guo Y, Chen Y, Song L, Yang J, Li L, Luo L
Oxidative medicine and cellular longevity 2022;2022:1330928
Oxidative medicine and cellular longevity 2022;2022:1330928
Exploring the impact of ovariectomy on hair growth: can ovariectomized mouse serve as a model for investigating female pattern hair loss in humans?
Togo S, Imanishi H, Hayashi M, Koyama M, Kira Y, Sugawara K, Tsuruta D
Medical molecular morphology 2022 Sep;55(3):210-226
Medical molecular morphology 2022 Sep;55(3):210-226
Oral exposure to DEHP may stimulate prostatic hyperplasia associated with upregulation of COX-2 and L-PGDS expressions in male adult rats.
Zhou P, Wu S, Huang D, Wang K, Su X, Yang R, Shao C, Wu J
Reproductive toxicology (Elmsford, N.Y.) 2022 Sep;112:160-170
Reproductive toxicology (Elmsford, N.Y.) 2022 Sep;112:160-170
Role of estrogen receptors in thyroid toxicity induced by mono (2-ethylhexyl) phthalate via endoplasmic reticulum stress: An in vitro mechanistic investigation.
Xu Q, Zhou L, Ri H, Li X, Zhang X, Qi W, Ye L
Environmental toxicology and pharmacology 2022 Nov;96:104007
Environmental toxicology and pharmacology 2022 Nov;96:104007
Validation of MAPK signalling pathway as a key role of paeoniflorin in the treatment of intrahepatic cholestasis of pregnancy based on network pharmacology and metabolomics.
Wang J, Wen J, Ma X, Yang J, Zhang Z, Xie S, Wei S, Jing M, Li H, Lang L, Zhou X, Zhao Y
European journal of pharmacology 2022 Nov 15;935:175331
European journal of pharmacology 2022 Nov 15;935:175331
Silibinin improves L-cell mass and function through an estrogen receptor-mediated antioxidative mechanism.
Wang J, Zhang L, Cao H, Shi X, Zhang X, Gao Z, Ikeda K, Yan T, Jia Y, Xu F
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 May;99:154022
Identification of Key Differentially Methylated/Expressed Genes and Pathways for Ovarian Endometriosis by Bioinformatics Analysis.
Zhang H, Wu J, Li Y, Jin G, Tian Y, Kang S
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Reproductive sciences (Thousand Oaks, Calif.) 2022 May;29(5):1630-1643
Cyanidin-3-O-glucoside ameliorates cadmium induced uterine epithelium proliferation in mice.
Yang D, Ran Y, Li X, Jiang X, Chen J, Sun J, Tian L, Teerds K, Bai W
Journal of hazardous materials 2022 Mar 5;425:127571
Journal of hazardous materials 2022 Mar 5;425:127571
Preimplantation triclosan exposure alters uterine receptivity through affecting tight junction protein†.
Dong G, Sun R, Zhang R, Qin Y, Lu C, Wang X, Xia Y, Du G
Biology of reproduction 2022 Jul 25;107(1):349-357
Biology of reproduction 2022 Jul 25;107(1):349-357
Upregulation of estrogen receptor alpha (ERα) expression in transgenic mice expressing human CYP4Z1.
Khayeka-Wandabwa C, Zhao J, Pathak JL, Wu H, Bureik M
Breast cancer research and treatment 2022 Jan;191(2):319-326
Breast cancer research and treatment 2022 Jan;191(2):319-326
Icaritin alleviates docetaxel-induced skin injury by suppressing reactive oxygen species via estrogen receptors.
Zou J, Xu MX, Li F, Wang YH, Li XQ, Yu DJ, Ma YJ, Zhang YY, Sun XD
Thoracic cancer 2022 Jan;13(2):190-201
Thoracic cancer 2022 Jan;13(2):190-201
Genistein reverses the effect of 17β-estradiol on exacerbating experimental occlusal interference-induced chronic masseter hyperalgesia in ovariectomised rats.
Liu Y, Zhang XY, Fan YY, Xu XX, Xie QF
Journal of oral rehabilitation 2022 Feb;49(2):237-248
Journal of oral rehabilitation 2022 Feb;49(2):237-248
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment.
Liang JJ, Yu WL, Yang L, Xie BH, Qin KM, Yin YP, Yan JJ, Gong S, Liu TY, Zhou HB, Hong K
European journal of medicinal chemistry 2022 Feb 5;229:114081
European journal of medicinal chemistry 2022 Feb 5;229:114081
Identification of endocrine-disrupting chemicals targeting the genes and pathways of genital anomalies in males.
Zhou X, Zhang X, Zhou X, Abulimiti G, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Yang J, Song N
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Ecotoxicology and environmental safety 2022 Dec 1;247:114241
Maternal Perinatal Exposure to Dibutyl Phthalate Promotes Ovarian Dysfunction in Adult Female Offspring via Downregulation of TGF-β2 and TGF-β3.
Zhang J, Zhou K, Cheng R, Yang M, Shen X, Luo X, Xu L
Reproductive sciences (Thousand Oaks, Calif.) 2022 Aug;29(8):2401-2413
Reproductive sciences (Thousand Oaks, Calif.) 2022 Aug;29(8):2401-2413
Discovery of Thieno[2,3-e]indazole Derivatives as Novel Oral Selective Estrogen Receptor Degraders with Highly Improved Antitumor Effect and Favorable Druggability.
Lu Z, Cao Y, Zhang D, Meng X, Guo B, Kong D, Yang Y
Journal of medicinal chemistry 2022 Apr 14;65(7):5724-5750
Journal of medicinal chemistry 2022 Apr 14;65(7):5724-5750
Exploration of the Danggui Buxue Decoction Mechanism Regulating the Balance of ESR and AR in the TP53-AKT Signaling Pathway in the Prevention and Treatment of POF.
Liu H, Yang H, Qin Z, Chen Y, Yu H, Li W, Zhu X, Cai J, Chen J, Zhang M
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4862164
Evidence-based complementary and alternative medicine : eCAM 2021;2021:4862164
Pan-Cancer Prognostic Role and Targeting Potential of the Estrogen-Progesterone Axis.
Shen YT, Huang X, Zhang G, Jiang B, Li CJ, Wu ZS
Frontiers in oncology 2021;11:636365
Frontiers in oncology 2021;11:636365
Co-exposure to BPA and DEHP enhances susceptibility of mammary tumors via up-regulating Esr1/HDAC6 pathway in female rats.
Zhang X, Cheng C, Zhang G, Xiao M, Li L, Wu S, Lu X
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Ecotoxicology and environmental safety 2021 Sep 15;221:112453
Expression of hormone receptors predicts survival and platinum sensitivity of high-grade serous ovarian cancer.
Tan J, Song C, Wang D, Hu Y, Liu D, Ma D, Gao Q
Bioscience reports 2021 May 28;41(5)
Bioscience reports 2021 May 28;41(5)
OTUD7B stabilizes estrogen receptor α and promotes breast cancer cell proliferation.
Tang J, Wu Z, Tian Z, Chen W, Wu G
Cell death & disease 2021 May 25;12(6):534
Cell death & disease 2021 May 25;12(6):534
Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors.
Liu W, Wang F, Li C, Otkur W, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Onodera S, Ikejima T
Journal of photochemistry and photobiology. B, Biology 2021 Mar;216:112147
Journal of photochemistry and photobiology. B, Biology 2021 Mar;216:112147
A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein.
Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, Zhou L, Li J, Jiang Z, Ding L, Zheng Z, Li S, Ye Q
Cell death discovery 2021 Jul 29;7(1):198
Cell death discovery 2021 Jul 29;7(1):198
The potential of Zishen Yutai pills to facilitate endometrial recovery and restore fertility after induced abortion in rats.
Li M, Ning N, Liu Y, Li X, Mei Q, Zhou J, Huang Q, Xiang W, Zhang L, Xu X
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Pharmaceutical biology 2021 Dec;59(1):1505-1516
Weighted gene coexpression network analysis reveals ESR1, FLNA and Furin as hub genes for DEHP-induced prepubertal testicular injury.
Chen J, Kang L, Wang J, Wu Y, Han L, Zheng X, Wei Y, Zhao T, Shen L, Long C, Wei G, Wu S
Reproductive toxicology (Elmsford, N.Y.) 2021 Dec;106:115-125
Reproductive toxicology (Elmsford, N.Y.) 2021 Dec;106:115-125
The "Matrisome" reveals the characterization of skin keloid microenvironment.
Zhang S, Liu B, Wang W, Lv L, Gao D, Chai M, Li M, Wu Z, Zhu Y, Ma J, Leng L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21237
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Apr;35(4):e21237
Role of estrogen receptor alpha in MEHP-induced proliferation and invasion of SH-SY5Y cells.
Guo S, Zhang B, Qi W, Cao X, Xu Y, Zhang X, Li X, Zhou L, Ye L
Toxicology 2021 Apr 15;453:152734
Toxicology 2021 Apr 15;453:152734
MiR-155-Mediated Deregulation of GPER1 Plays an Important Role in the Gender Differences Related to Inflammatory Bowel Disease.
Shao X, Li J, Xu F, Chen D, Liu K
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 2020;2020:8811477
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 2020;2020:8811477
Wntless (Wls): A Prognostic Index for Progression and Patient Survival of Breast Cancer.
Zheng D, Jiang C, Yan N, Miao Y, Wang K, Gao G, Jiao Y, Zhang X, He M, Yang Z
OncoTargets and therapy 2020;13:12649-12659
OncoTargets and therapy 2020;13:12649-12659
InvivoPen: A novel plasma source for in vivo cancer treatment.
Zhou X, Cai D, Xiao S, Ning M, Zhou R, Zhang S, Chen X, Ostrikov K, Dai X
Journal of Cancer 2020;11(8):2273-2282
Journal of Cancer 2020;11(8):2273-2282
Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features.
Mei Y, Cai D, Dai X
Journal of Cancer 2020;11(5):1162-1169
Journal of Cancer 2020;11(5):1162-1169
Neuroprotective effects of vitamin D and 17ß-estradiol against ovariectomy-induced neuroinflammation and depressive-like state: Role of the AMPK/NF-κB pathway.
Zhang WY, Guo YJ, Wang KY, Chen LM, Jiang P
International immunopharmacology 2020 Sep;86:106734
International immunopharmacology 2020 Sep;86:106734
TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α.
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, Wu G
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Neoplasia (New York, N.Y.) 2020 Sep;22(9):343-351
Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration.
Wang X, Lin Y, Zheng Y
Molecular medicine reports 2020 Sep;22(3):2318-2328
Molecular medicine reports 2020 Sep;22(3):2318-2328
Effect of liquiritin on neuroendocrine-immune network in menopausal rat model.
Lan XY, Yu H, Chen QJ, Zhai S, Zhang CF, Li F, Wang CZ, Yuan CS
Phytotherapy research : PTR 2020 Oct;34(10):2665-2674
Phytotherapy research : PTR 2020 Oct;34(10):2665-2674
Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression.
Long X, Gao Y, Liu W, Liu X, Hayashi T, Mizuno K, Hattori S, Ikejima T
Molecular and cellular biochemistry 2020 Nov;474(1-2):243-261
Molecular and cellular biochemistry 2020 Nov;474(1-2):243-261
Propofol exerts neuroprotective functions by down-regulating microRNA-19a in glutamic acid-induced PC12 cells.
Yu S, Xin W, Jiang Q, Li A
BioFactors (Oxford, England) 2020 Nov;46(6):934-942
BioFactors (Oxford, England) 2020 Nov;46(6):934-942
The Potential Effect of Fucoidan on Inhibiting Epithelial-to-Mesenchymal Transition, Proliferation, and Increase in Apoptosis for Endometriosis Treatment: In Vivo and In Vitro Study.
Chang LC, Chiang YF, Chen HY, Huang YJ, Liu AC, Hsia SM
Biomedicines 2020 Nov 22;8(11)
Biomedicines 2020 Nov 22;8(11)
Targeting claudin-4 enhances chemosensitivity in breast cancer.
Luo Y, Kishi S, Sasaki T, Ohmori H, Fujiwara-Tani R, Mori S, Goto K, Nishiguchi Y, Mori T, Kawahara I, Kondoh M, Kuniyasu H
Cancer science 2020 May;111(5):1840-1850
Cancer science 2020 May;111(5):1840-1850
The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats.
Ren L, Liu W, Wang C, Yang Y, Huang X, Wang C, Li Y
Journal of ethnopharmacology 2020 May 23;254:112572
Journal of ethnopharmacology 2020 May 23;254:112572
RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination.
Ren Y, Xu X, Mao CY, Han KK, Xu YJ, Cao BY, Zhang ZB, Sethi G, Tang XW, Mao XL
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Acta pharmacologica Sinica 2020 Mar;41(3):394-403
Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells.
Chu C, Gao X, Li X, Zhang X, Ma R, Jia Y, Li D, Wang D, Xu F
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
Biomolecules & therapeutics 2020 Mar 1;28(2):163-171
miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling.
Chen GH, Zhang XL, Chen H, Lin H, Wu HJ, Lin H, Huang GZ
The journal of gene medicine 2020 Jun;22(6):e3174
The journal of gene medicine 2020 Jun;22(6):e3174
Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome.
Sun M, Sun B, Qiao S, Feng X, Li Y, Zhang S, Lin Y, Hou L
Fertility and sterility 2020 Jun;113(6):1275-1285.e2
Fertility and sterility 2020 Jun;113(6):1275-1285.e2
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, Yuan C, Xu J, Yan L, Hao H
International immunopharmacology 2020 Aug;85:106625
International immunopharmacology 2020 Aug;85:106625
AGR3 promotes estrogen receptor-positive breast cancer cell proliferation in an estrogen-dependent manner.
Jian L, Xie J, Guo S, Yu H, Chen R, Tao K, Yang C, Li K, Liu S
Oncology letters 2020 Aug;20(2):1441-1451
Oncology letters 2020 Aug;20(2):1441-1451
Vaccarin promotes proliferation of and milk synthesis in bovine mammary epithelial cells through the Prl receptor-PI3K signaling pathway.
Yu Y, Yuan X, Li P, Wang Y, Yu M, Gao X
European journal of pharmacology 2020 Aug 5;880:173190
European journal of pharmacology 2020 Aug 5;880:173190
The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A.
Wu S, Huang D, Su X, Yan H, Ma A, Li L, Wu J, Sun Z
Scientific reports 2020 Aug 4;10(1):13108
Scientific reports 2020 Aug 4;10(1):13108
Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells.
Wang J, Zhang X, Zhang L, Yan T, Wu B, Xu F, Jia Y
European journal of pharmacology 2020 Aug 15;881:173236
European journal of pharmacology 2020 Aug 15;881:173236
TP53 Mutations Promote Immunogenic Activity in Breast Cancer.
Liu Z, Jiang Z, Gao Y, Wang L, Chen C, Wang X
Journal of oncology 2019;2019:5952836
Journal of oncology 2019;2019:5952836
Dual targeting of estrogen receptor α and estrogen-related receptor α: a novel endocrine therapy for endometrial cancer.
Mao X, Dong B, Gao M, Ruan G, Huang M, Braicu EI, Sehouli J, Sun P
OncoTargets and therapy 2019;12:6757-6767
OncoTargets and therapy 2019;12:6757-6767
Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity.
Fan H, Chen S, Gao B, Ding S, Zhao Q, Li C, Asakawa T
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1287-1295
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1287-1295
ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control.
Dai X, Mei Y, Chen X, Cai D
Frontiers in genetics 2019;10:790
Frontiers in genetics 2019;10:790
Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer.
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, Wang J, Bao Y
Pharmacological research 2019 Sep;147:104387
Pharmacological research 2019 Sep;147:104387
Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression.
Li H, Wu W, He X, Cao C, Yu X, Zeng Y, Li L
Bioscience reports 2019 Sep 30;39(9)
Bioscience reports 2019 Sep 30;39(9)
Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha.
Sun Y, Yang J, Liu W, Yao G, Xu F, Hayashi T, Onodera S, Ikejima T
Molecular and cellular biochemistry 2019 Oct;460(1-2):81-92
Molecular and cellular biochemistry 2019 Oct;460(1-2):81-92
Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats.
Wu S, Huang D, Su X, Yan H, Wu J, Sun Z
Toxicology and industrial health 2019 Oct;35(10):647-659
Toxicology and industrial health 2019 Oct;35(10):647-659
ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis.
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J
Molecular medicine reports 2019 May;19(5):3469-3476
Molecular medicine reports 2019 May;19(5):3469-3476
Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus.
Liu L, Yan J, Ge F, Xu X, Lu J, Shi H, Li S, Zhao Y, Zhang C
Molecular medicine reports 2019 Jul;20(1):332-340
Molecular medicine reports 2019 Jul;20(1):332-340
Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy.
Andrade FO, Nguyen NM, Warri A, Hilakivi-Clarke L
Scientific reports 2019 Dec 30;9(1):20271
Scientific reports 2019 Dec 30;9(1):20271
Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ(1-42) -induced reactive oxygen species/reactive nitrogen species generation.
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Hattori S, Ushiki-Kaku Y, Onodera S, Tashiro SI, Ikejima T
Phytotherapy research : PTR 2019 Apr;33(4):998-1009
Phytotherapy research : PTR 2019 Apr;33(4):998-1009
Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice.
Shen D, Tian L, Shen T, Sun H, Liu P
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(6):2261-2277
Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines.
Wan S, Jiang J, Zheng C, Wang N, Zhai X, Fei X, Wu R, Jiang X
Cell death discovery 2018;4:49
Cell death discovery 2018;4:49
Rutin attenuates cerebral ischemia-reperfusion injury in ovariectomized rats via estrogen-receptor-mediated BDNF-TrkB and NGF-TrkA signaling.
Liu H, Zhong L, Zhang Y, Liu X, Li J
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):672-681
Biochemistry and cell biology = Biochimie et biologie cellulaire 2018 Oct;96(5):672-681
Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.
Ge L, Cui Y, Cheng K, Han J
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Molecules (Basel, Switzerland) 2018 Oct 11;23(10)
Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring.
Zhu J, Jia YL, Luo YW, Huang DY, Shao CC, Li L, Zhou L, Sun ZY
International urology and nephrology 2018 Nov;50(11):1963-1973
International urology and nephrology 2018 Nov;50(11):1963-1973
Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity.
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Onodera S, Tashiro SI, Ikejima T
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:344-353
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jun;102:344-353
Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats.
Huang DY, Zheng CC, Pan Q, Wu SS, Su X, Li L, Wu JH, Sun ZY
Scientific reports 2018 Jan 11;8(1):490
Scientific reports 2018 Jan 11;8(1):490
EZH2 inhibition sensitizes tamoxifen‑resistant breast cancer cells through cell cycle regulation.
Chen S, Yao F, Xiao Q, Liu Q, Yang Y, Li X, Jiang G, Kuno T, Fang Y
Molecular medicine reports 2018 Feb;17(2):2642-2650
Molecular medicine reports 2018 Feb;17(2):2642-2650
17beta-estradiol Attenuates TNF-α-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-κB Pathway.
Li P, Gan Y, Xu Y, Wang L, Ouyang B, Zhang C, Luo L, Zhao C, Zhou Q
International journal of biological sciences 2017;13(2):145-156
International journal of biological sciences 2017;13(2):145-156
HPK1 positive expression associated with longer overall survival in patients with estrogen receptor-positive invasive ductal carcinoma‑not otherwise specified.
Wang J, Song L, Yang S, Zhang W, Lu P, Li S, Li H, Wang L
Molecular medicine reports 2017 Oct;16(4):4634-4642
Molecular medicine reports 2017 Oct;16(4):4634-4642
Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer.
Fan S, Liao Y, Liu C, Huang Q, Liang H, Ai B, Fu S, Zhou S
Oncotarget 2017 Aug 22;8(34):56443-56459
Oncotarget 2017 Aug 22;8(34):56443-56459
MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3.
Fu Y, Xiong J
Croatian medical journal 2016 Oct 31;57(5):457-464
Croatian medical journal 2016 Oct 31;57(5):457-464
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement.
Chen L, Lv D, Wang D, Chen X, Zhu Z, Cao Y, Chai Y
Molecular bioSystems 2016 Oct 18;12(11):3347-3356
Molecular bioSystems 2016 Oct 18;12(11):3347-3356
miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor.
Wang Q, Xu C, Zhao Y, Xu Z, Zhang Y, Jiang J, Yan B, Gu D, Wu M, Wang Y, Liu H
Stem cells and development 2016 Mar 1;25(5):415-26
Stem cells and development 2016 Mar 1;25(5):415-26
Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia.
Song L, Shen W, Zhang H, Wang Q, Wang Y, Zhou Z
Bosnian journal of basic medical sciences 2016 Jul 2;16(3):201-8
Bosnian journal of basic medical sciences 2016 Jul 2;16(3):201-8
Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins.
Qin Z, Zheng H, Zhou L, Ou Y, Huang B, Yan B, Qin Z, Yang C, Su Y, Bai X, Guo J, Lin J
Scientific reports 2016 Jan 22;6:19587
Scientific reports 2016 Jan 22;6:19587
ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells.
Zheng N, Liu L, Liu W, Zhang P, Huang H, Zang L, Hayashi T, Tashiro S, Onodera S, Xia M, Ikejima T
Archives of biochemistry and biophysics 2016 Feb 1;591:141-9
Archives of biochemistry and biophysics 2016 Feb 1;591:141-9
Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle.
Ideta A, Yamashita S, Seki-Soma M, Yamaguchi R, Chiba S, Komaki H, Ito T, Konishi M, Aoyagi Y, Sendai Y
Scientific reports 2016 Apr 27;6:24983
Scientific reports 2016 Apr 27;6:24983
Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats.
Fu C, Xu D, Wang CY, Jin Y, Liu Q, Meng Q, Liu KX, Sun HJ, Liu MZ
Journal of cellular physiology 2015 Sep;230(9):2184-201
Journal of cellular physiology 2015 Sep;230(9):2184-201
ERα down-regulation plays a key role in silibinin-induced autophagy and apoptosis in human breast cancer MCF-7 cells.
Zheng N, Zhang P, Huang H, Liu W, Hayashi T, Zang L, Zhang Y, Liu L, Xia M, Tashiro S, Onodera S, Ikejima T
Journal of pharmacological sciences 2015 Jul;128(3):97-107
Journal of pharmacological sciences 2015 Jul;128(3):97-107
Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines.
Zhang C, Peng J, Wu S, Jin Y, Xia F, Wang C, Liu K, Sun H, Liu M
Journal of biomedical science 2014 Apr 17;21(1):30
Journal of biomedical science 2014 Apr 17;21(1):30
MicroRNA 'signature' during estrogen-mediated mammary carcinogenesis and its reversal by ellagic acid intervention.
Munagala R, Aqil F, Vadhanam MV, Gupta RC
Cancer letters 2013 Oct 10;339(2):175-84
Cancer letters 2013 Oct 10;339(2):175-84
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 21244-1-AP( ER Antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 21244-1-AP(ESR1 antibody) at dilution of 1:25 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ER antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ER. This antibody recognizes human,mouse,rat antigen. The ER antibody has been validated for the following applications: ELISA, IHC, WB analysis.
