ABIN197221

antibody from antibodies-online

Targeting: ESR1 ER-alpha, Era, ESR, NR3A1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN197221

Provider

antibodies-online

Product name

anti-Estrogen Receptor 1 (ESR1) (AA 165-169) antibody

Antibody type

Polyclonal

Description

Affinity Chromatography using epitope-specific peptide

Reactivity

Human, Mouse

Host

Rabbit

Epitope

AA 165-169

Vial size

50 μL

Storage

Store the antibody (in aliquots) at -20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.

Shah YM, Rowan BG
Molecular endocrinology (Baltimore, Md.) 2005 Mar;19(3):732-48

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance.

Campbell RA, Bhat-Nakshatri P, Patel NM, Constantinidou D, Ali S, Nakshatri H
The Journal of biological chemistry 2001 Mar 30;276(13):9817-24

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Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ
Cancer research 2001 Aug 15;61(16):5985-91

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Activation of estrogen receptor alpha by S118 phosphorylation involves a ligand-dependent interaction with TFIIH and participation of CDK7.

Chen D, Riedl T, Washbrook E, Pace PE, Coombes RC, Egly JM, Ali S
Molecular cell 2000 Jul;6(1):127-37