ABIN967786

antibody from antibodies-online

Targeting: ERBB2 CD340, HER-2, HER2, NEU, NGL

Western blot (Recommended by provider)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

ABIN967786

Provider

antibodies-online

Product name

anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (AA 182-373) antibody

Antibody type

Monoclonal

Antigen

Rat ErbB2

Description

Purified from tissue culture supernatant or ascites by affinity chromatography.

Reactivity

Rat

Host

Mouse

Epitope

AA 182-373

Isotype

IgG

Antibody clone number

BF12

Vial size

50 μg

Concentration

250 μg/ml

Storage

-20°C

References

Submitted references

Basolateral targeting of ERBB2 is dependent on a novel bipartite juxtamembrane sorting signal but independent of the C-terminal ERBIN-binding domain.

Dillon C, Creer A, Kerr K, Kümin A, Dickson C
Molecular and cellular biology 2002 Sep;22(18):6553-63

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Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2.

Piechocki MP, Pilon SA, Wei WZ
Journal of immunology (Baltimore, Md. : 1950) 2001 Sep 15;167(6):3367-74

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Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90.

Xu W, Mimnaugh E, Rosser MF, Nicchitta C, Marcu M, Yarden Y, Neckers L
The Journal of biological chemistry 2001 Feb 2;276(5):3702-8

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ERBB-2 (HER2/neu) gene copy number, p185HER-2 overexpression, and intratumor heterogeneity in human breast cancer.

Szöllösi J, Balázs M, Feuerstein BG, Benz CC, Waldman FM
Cancer research 1995 Nov 15;55(22):5400-7

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Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling.

Graus-Porta D, Beerli RR, Hynes NE
Molecular and cellular biology 1995 Mar;15(3):1182-91