Tissue expression
Cell line expression

ERBB2

gene product
CD340, HER-2, HER2, NEU, NGL 
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]
More gene data

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6519 antibodies from 61 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
5 antibodies
Invitrogen Antibodies
234 antibodies
R&D Systems
47 antibodies
Novus Biologicals
376 antibodies
OriGene
393 antibodies
antibodies-online
1838 antibodies
GeneTex
51 antibodies
NSJ Bioreagents
41 antibodies
Abnova Corporation
43 antibodies
Atlas Antibodies
5 antibodies
Acris Antibodies GmbH
124 antibodies
Biorbyt
249 antibodies
Abgent
51 antibodies
Boster Biological Technology
13 antibodies
NovoPro Bioscience Inc.
56 antibodies
LifeSpan BioSciences, Inc.
660 antibodies
Affinity Biosciences
21 antibodies
Wuhan Fine Biotech Co., Ltd.
3 antibodies
Cell Signaling Technology, Inc
15 antibodies
Aviva Systems Biology
41 antibodies
Cusabio Biotech Co., Ltd
30 antibodies
Signalway Antibody LLC
7 antibodies
St John's Laboratory
37 antibodies
HUABIO Research
2 antibodies
ProSci
16 antibodies
Bioworld Technology, Inc
10 antibodies
SignalChem
2 antibodies
Bethyl Laboratories
4 antibodies
QED Bioscience
4 antibodies
BioLegend
18 antibodies
Enzo Life Sciences
2 antibodies
RabMAbs
13 antibodies
FabGennix
12 antibodies
Abbkine Scientific Co.Ltd.
17 antibodies
Sino Biological Inc.
16 antibodies
Antibodies.com
2 antibodies
MilliporeSigma / Merck KGaA
20 antibodies
MyBioSource
63 antibodies
Creative Diagnostics
35 antibodies
Leading Biology
62 antibodies
Abbexa
76 antibodies
ABEOMICS Inc.
4 antibodies
Creative Biolabs
950 antibodies
EMD Millipore
14 antibodies
GenWay
23 antibodies
Abbiotec
5 antibodies
RayBiotech, Inc.
9 antibodies
Rockland Immunochemicals, Inc.
3 antibodies
SICGEN
1 antibody
United States Biological
552 antibodies
Spring Bioscience
20 antibodies
Absolute Antibody
20 antibodies
Miltenyi Biotec
10 antibodies
DB Biotech
1 antibody
Nordic BioSite
4 antibodies
eBioscience, An Affymetrix Company
3 antibodies
Exalpha Biologicals, Inc.
3 antibodies
CPTAC
4 antibodies
MedChemExpress LLC
2 antibodies