Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN362015 - Provider product page
- Provider
- antibodies-online
- Proper citation
- Antibodies-Online Cat#ABIN362015, RRID:AB_10952766
- Product name
- anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pTyr877) antibody
- Antibody type
- Polyclonal
- Antigen
- Peptide sequence around phosphorylation site of pTyr877 (T-E-Y (p) -H-A) derived from Human HER2. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.
- Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific phosphopeptide. The antibody against non-phosphopeptide was removedby chromatogramphy using non-phosphopeptide corresponding to the phosphorrylation site.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- pTyr877
- Isotype
- IgG
- Vial size
- 50 μL
- Concentration
- 1 mg/mL
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Submitted references More about: prognostic importance of low c-erbB2 expression in breast tumors.
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.
Dittadi R, Gion M
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Journal of the National Cancer Institute 2000 Sep 6;92(17):1443-4
Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers.
Muthuswamy SK, Gilman M, Brugge JS
Molecular and cellular biology 1999 Oct;19(10):6845-57
Molecular and cellular biology 1999 Oct;19(10):6845-57
Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: a mechanism of interreceptor kinase activation and transphosphorylation.
Qian X, LeVea CM, Freeman JK, Dougall WC, Greene MI
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 15;91(4):1500-4
Proceedings of the National Academy of Sciences of the United States of America 1994 Feb 15;91(4):1500-4
No comments: Submit comment
No validations: Submit validation data