Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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- Product number
- ABIN967459 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (AA 1242-1255) antibody
- Antibody type
- Monoclonal
- Antigen
- Human c-erbB-2
- Description
- Purified from tissue culture supernatant or ascites by affinity chromatography.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1242-1255
- Isotype
- IgG
- Antibody clone number
- 3B5
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- 4°C
Submitted references Optimization of immunohistochemical detection of ERBB2 in human breast cancer: impact of fixation.
A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling.
Expression of neu/c-erbB-2 in human brain tumors.
Relationships between epidermal growth factor receptor (EGF-R) and other predictors of prognosis in breast carcinomas. An immunohistochemical study.
Detection of c-erbB-2 activation in paraffin-embedded tissue by immunohistochemistry.
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines.
Amplification and expression of the c-erb B-2/neu proto-oncogene in human bladder cancer.
Study of neu-protein expression in mammary Paget's disease with and without underlying breast carcinoma and in extramammary Paget's disease.
Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer.
Penault-Llorca F, Adelaïde J, Houvenaeghel G, Hassoun J, Birnbaum D, Jacquemier J
The Journal of pathology 1994 May;173(1):65-75
The Journal of pathology 1994 May;173(1):65-75
A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling.
Carraway KL 3rd, Cantley LC
Cell 1994 Jul 15;78(1):5-8
Cell 1994 Jul 15;78(1):5-8
Expression of neu/c-erbB-2 in human brain tumors.
Schwechheimer K, Läufle RM, Schmahl W, Knödlseder M, Fischer H, Höfler H
Human pathology 1994 Aug;25(8):772-80
Human pathology 1994 Aug;25(8):772-80
Relationships between epidermal growth factor receptor (EGF-R) and other predictors of prognosis in breast carcinomas. An immunohistochemical study.
Martinazzi M, Crivelli F, Zampatti C, Martinazzi S
Pathologica 1993 Nov-Dec;85(1100):637-44
Pathologica 1993 Nov-Dec;85(1100):637-44
Detection of c-erbB-2 activation in paraffin-embedded tissue by immunohistochemistry.
Singleton TP, Niehans GA, Gu F, Litz CE, Hagen K, Qiu Q, Kiang DT, Strickler JG
Human pathology 1992 Oct;23(10):1141-50
Human pathology 1992 Oct;23(10):1141-50
A monoclonal antibody against the c-erbB-2 protein enhances the cytotoxicity of cis-diamminedichloroplatinum against human breast and ovarian tumor cell lines.
Hancock MC, Langton BC, Chan T, Toy P, Monahan JJ, Mischak RP, Shawver LK
Cancer research 1991 Sep 1;51(17):4575-80
Cancer research 1991 Sep 1;51(17):4575-80
Amplification and expression of the c-erb B-2/neu proto-oncogene in human bladder cancer.
Zhau HE, Zhang X, von Eschenbach AC, Scorsone K, Babaian RJ, Ro JY, Hung MC
Molecular carcinogenesis 1990;3(5):254-7
Molecular carcinogenesis 1990;3(5):254-7
Study of neu-protein expression in mammary Paget's disease with and without underlying breast carcinoma and in extramammary Paget's disease.
Meissner K, Rivière A, Haupt G, Löning T
The American journal of pathology 1990 Dec;137(6):1305-9
The American journal of pathology 1990 Dec;137(6):1305-9
Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer.
van de Vijver MJ, Peterse JL, Mooi WJ, Wisman P, Lomans J, Dalesio O, Nusse R
The New England journal of medicine 1988 Nov 10;319(19):1239-45
The New England journal of medicine 1988 Nov 10;319(19):1239-45
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Supportive validation
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- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemical staining for c-erbB-2. Formalin-fixed, paraffin-embedded tissue section of human breast cancer stained with Anti-Human c-ErbB-2 (clone 3B5, ABIN967459) using a DAB chromogen and Hematoxylin counterstain.