abx011056

antibody from Abbexa

Targeting: KLK3 APS, PSA

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

abx011056

Provider

Abbexa

Product name

Prostate-Specific Antigen (KLK3) Antibody

Antibody type

Monoclonal

Description

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Vial size

100 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.