KLK3

gene product
APS, PSA
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
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AntibodyRefsTypeWBELICCIPIHCFC
R&D Systems
6 antibodies
Novus Biologicals
132 antibodies
NovoPro Bioscience Inc.
17 antibodies
NSJ Bioreagents
10 antibodies
antibodies-online
802 antibodies