Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [4]
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Validation data
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- Product number
- V2253 - Provider product page
- Provider
- NSJ Bioreagents
- Product name
- gp100 Antibody
- Antibody type
- Monoclonal
- Antigen
- The extract of pigmented melanoma metastases from lymph nodes was used as the immunogen for this gp100 antibody.
- Description
- Protein G purified antibody
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antibody clone number
- HMB45
- Vial size
- 20 µg, 100 µg (with sodium azide), 100 µg (without sodium azide), 7 ml (prediluted for IHC use, if applicable)
- Storage
- Store the gp100 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Submitted references Antibody αPEP13h reacts with lymphangioleiomyomatosis cells in lung nodules.
CD133⁺ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: significance for melanoma treatment.
Comparative genomic hybridization in a case of melanoma that loses expression of S100, HMB45, Melan A and tyrosinase in metastasis.
Pigmented oral carcinoma in situ: a case report and literature review.
Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration.
Diagnostic and prognostic biomarkers in melanoma.
Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update.
Investigation of cAMP microdomains as a path to novel cancer diagnostics.
Valencia JC, Steagall WK, Zhang Y, Fetsch P, Abati A, Tsukada K, Billings E, Hearing VJ, Yu ZX, Pacheco-Rodriguez G, Moss J
Chest 2015 Mar;147(3):771-7
Chest 2015 Mar;147(3):771-7
CD133⁺ melanoma subpopulation acquired resistance to caffeic acid phenethyl ester-induced apoptosis is attributed to the elevated expression of ABCB5: significance for melanoma treatment.
El-Khattouti A, Sheehan NT, Monico J, Drummond HA, Haikel Y, Brodell RT, Megahed M, Hassan M
Cancer letters 2015 Feb 1;357(1):83-104
Cancer letters 2015 Feb 1;357(1):83-104
Comparative genomic hybridization in a case of melanoma that loses expression of S100, HMB45, Melan A and tyrosinase in metastasis.
Guo R, Wang X, Chen J, Gillies E, Fung KM, Li S, Hassell LA
International journal of clinical and experimental pathology 2014;7(1):468-73
International journal of clinical and experimental pathology 2014;7(1):468-73
Pigmented oral carcinoma in situ: a case report and literature review.
Matsumoto N, Kitano T, Oki H, Omagari D, Matsue Y, Okudera M, Yamamura T, Nishikawa Y, Nishimura S, Asano M, Komiyama K
Oral surgery, oral medicine, oral pathology and oral radiology 2014 Sep;118(3):e79-83
Oral surgery, oral medicine, oral pathology and oral radiology 2014 Sep;118(3):e79-83
Human melanoma metastases demonstrate nonstochastic site-specific antigen heterogeneity that correlates with T-cell infiltration.
Bartlett EK, Fetsch PA, Filie AC, Abati A, Steinberg SM, Wunderlich JR, White DE, Stephens DJ, Marincola FM, Rosenberg SA, Kammula US
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 15;20(10):2607-16
Clinical cancer research : an official journal of the American Association for Cancer Research 2014 May 15;20(10):2607-16
Diagnostic and prognostic biomarkers in melanoma.
Weinstein D, Leininger J, Hamby C, Safai B
The Journal of clinical and aesthetic dermatology 2014 Jun;7(6):13-24
The Journal of clinical and aesthetic dermatology 2014 Jun;7(6):13-24
Value of melanocytic-associated immunohistochemical markers in the diagnosis of malignant melanoma: a review and update.
Ordóñez NG
Human pathology 2014 Feb;45(2):191-205
Human pathology 2014 Feb;45(2):191-205
Investigation of cAMP microdomains as a path to novel cancer diagnostics.
Desman G, Waintraub C, Zippin JH
Biochimica et biophysica acta 2014 Dec;1842(12 Pt B):2636-45
Biochimica et biophysica acta 2014 Dec;1842(12 Pt B):2636-45
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Supportive validation
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of human melanoma (10X) with gp100 antibody (HMB45).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of human melanoma (20X) with gp100 antibody (HMB45).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of human melanoma with gp100 antibody (HMB45).
- Submitted by
- NSJ Bioreagents (provider)
- Main image
- Experimental details
- IHC staining of testis with gp100 antibody (HMB45).