PMEL

gene product
D12S53E, gp100, Pmel17, SI, SIL, SILV
This gene encodes a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. This protein undergoes a complex pattern of prosttranslational processing and modification that is essential to the proper functioning of the protein. A secreted form of this protein that is released by proteolytic ectodomain shedding may be used as a melanoma-specific serum marker. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2011]
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1035 antibodies from 33 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
220 antibodies
Atlas Antibodies
1 antibody
NovoPro Bioscience Inc.
6 antibodies
Abgent
6 antibodies
Invitrogen Antibodies
5 antibodies
GeneTex
14 antibodies
NSJ Bioreagents
14 antibodies
OriGene
39 antibodies
antibodies-online
463 antibodies