Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB12093 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12093, RRID:AB_1676304
- Product name
- NPC1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of NPC1.
- Storage
- Store at 4°C for short term. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster.
Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.
Burke KT, Colvin PL, Myatt L, Graf GA, Schroeder F, Woollett LA
Journal of lipid research 2009 Jun;50(6):1146-55
Journal of lipid research 2009 Jun;50(6):1146-55
Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
Frolov A, Srivastava K, Daphna-Iken D, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2001 Dec 7;276(49):46414-21
The Journal of biological chemistry 2001 Dec 7;276(49):46414-21
Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.
Millard EE, Srivastava K, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2000 Dec 8;275(49):38445-51
The Journal of biological chemistry 2000 Dec 8;275(49):38445-51
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Supportive validation
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- Abnova Corporation (provider)
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- Experimental details
- Western blot analysis of NPC1 in 20 ug of human fibroblast cell lysate with NPC1 polyclonal antibody (Cat # PAB12093).