Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- GTX30687 - Provider product page
- Provider
- GeneTex
- Proper citation
- GeneTex Cat#GTX30687, RRID:AB_625985
- Product name
- NPC1 antibody
- Antibody type
- Polyclonal
- Reactivity
- Human, Mouse, Rat, Hamster, Porcine, Simian
- Host
- Rabbit
Submitted references Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function.
Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.
Frolov A, Srivastava K, Daphna-Iken D, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2001 Dec 7;276(49):46414-21
The Journal of biological chemistry 2001 Dec 7;276(49):46414-21
Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis.
Millard EE, Srivastava K, Traub LM, Schaffer JE, Ory DS
The Journal of biological chemistry 2000 Dec 8;275(49):38445-51
The Journal of biological chemistry 2000 Dec 8;275(49):38445-51
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Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Western Blot: Niemann-Pick C1 Antibody [GTX30687] - Detection of human NPC1 in 20 μg of human fibroblast cell lysate.
Supportive validation
- Submitted by
- GeneTex (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Niemann-Pick C1 Antibody [GTX30687] - Staining of human brain, cortex, neurons and astrocytes.