CABT-B11229

antibody from Creative Diagnostics

Targeting: RNF139 HRCA1, RCA1, TRC8

Western blot (Recommended by provider)

ELISA (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B11229

Provider

Creative Diagnostics

Product name

Mouse anti-Human RNF139 monoclonal antibody, clone 4E20

Antibody type

Monoclonal

Description

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]

Reactivity

Human

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4.00E+20

Storage

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.