RNF139

gene product
HRCA1, RCA1, TRC8
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]
More gene data

Featured antibodies

Antibodies

 

Filters

Antibodypedia Validation Initiative

Validation method

Application

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

  or   Clear
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider
Validated within AVI
Eligible for validation within AVI
137 antibodies from 25 providers.

Antibody properties

Applications

or Cancel
AntibodyRefsTypeAVIWBELICCIPIHCFC
Abnova Corporation
6 antibodies
Novus Biologicals
5 antibodies
antibodies-online
36 antibodies
LifeSpan BioSciences, Inc.
20 antibodies
Abgent
3 antibodies
Acris Antibodies GmbH
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
1 antibody
GeneTex
2 antibodies
Aviva Systems Biology
2 antibodies
Arigo
1 antibody
Atlas Antibodies
1 antibody
Invitrogen Antibodies
3 antibodies
Biorbyt
6 antibodies
ProSci
2 antibodies
St John's Laboratory
1 antibody
OriGene
3 antibodies
Creative Diagnostics
2 antibodies
MyBioSource
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
20 antibodies
Sigma-Aldrich
4 antibodies
Creative Biolabs
1 antibody