RNF139

gene product
HRCA1, RCA1, TRC8
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]
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antibodies-online
55 antibodies
Abnova Corporation
6 antibodies
Novus Biologicals
5 antibodies
Atlas Antibodies
1 antibody
LifeSpan BioSciences, Inc.
20 antibodies
Abgent
3 antibodies
Acris Antibodies GmbH
1 antibody
Antibodies.com
1 antibody
Everest Biotech
1 antibody
NSJ Bioreagents
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Biorbyt
13 antibodies
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2 antibodies
Aviva Systems Biology
2 antibodies
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3 antibodies
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St John's Laboratory
1 antibody
Creative Biolabs
5 antibodies
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Creative Diagnostics
3 antibodies
MyBioSource
2 antibodies
RayBiotech, Inc.
1 antibody
United States Biological
20 antibodies
Sigma-Aldrich
4 antibodies