Tissue expression
Cell line expression
ANAPC10
gene productAPC10, DKFZP564L0562, DOC1
ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]). [supplied by OMIM, Feb 2011]
Featured antibodies
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0 references | Polyclonal |
ICC
IHC |
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0 references | Polyclonal |
WB
EL ICC
IHC |