Antibody data
- Antibody Data
- Antigen structure
- References [103]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 66169-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- Caspase 9/p35/p10 antibody
- Antibody type
- Monoclonal
- Description
- Caspase 9/p35/p10 antibody (Cat. #66169-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B7G2
- Vial size
- 20ul, 150ul
Submitted references Vitamin C Inhibited Pulmonary Metastasis through Activating Nrf2/HO-1 Pathway.
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer.
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Echinacoside alleviates glucocorticoid induce osteonecrosis of femoral head in rats through PI3K/AKT/FOXO1 pathway.
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Reactive Oxygen Species-Mediated Mitophagy and Cell Apoptosis are Involved in the Toxicity of Aluminum Chloride Exposure in GC-2spd.
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
3'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma.
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer.
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells: screening results using weighted gene co-expression network analysis.
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
Establishment of sheep nasal mucosa explant model and its application in antiviral research.
Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway.
Targeting HSP90 with picropodophyllin suppresses gastric cancer tumorigenesis by disrupting the association of HSP90 and AKT.
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer.
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway.
GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cells.
The protective mechanism of a novel polysaccharide from Lactobacillus-fermented Nostoc commune Vauch. on attenuating cadmium-induced kidney injury in mice.
Simple Nano-Luciferase-Based Assay for the Rapid and High-Throughput Detection of SARS-CoV-2 3C-Like Protease.
PM2.5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway.
MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells.
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway.
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Chemical Composition, Antitumor Properties, and Mechanism of the Essential Oil from Plagiomnium acutum T. Kop.
Ginsenoside Rd ameliorates high glucose-induced retinal endothelial injury through AMPK-STRT1 interdependence.
Protective Effect of Resveratrol on Immortalized Duck Intestinal Epithelial Cells Exposed to H(2)O(2).
Hernandezine Regulates Proliferation and Autophagy-Induced Apoptosis in Melanoma Cells.
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system.
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
LS-HB-Mediated Photodynamic Therapy Inhibits Proliferation and Induces Cell Apoptosis in Melanoma.
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
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Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI.
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Sonodynamic Effects of a Novel Ether-Group Modified Porphyrin Derivative Combined With Pulsed Low-Intensity Ultrasound on PC-9 Cells.
Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits.
m(6)A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
The inhibitory effect Polygonum Cillinerve polysaccharide on transmissible gastroenteritis virus of swine.
Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells.
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
Integration of exonuclease III-powered three-dimensional DNA walker with single-molecule detection for multiple initiator caspases assay.
A Natural Degradant of Curcumin, Feruloylacetone Inhibits Cell Proliferation via Inducing Cell Cycle Arrest and a Mitochondrial Apoptotic Pathway in HCT116 Colon Cancer Cells.
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway.
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Proanthocyanidin B2 inhibits proliferation and induces apoptosis of osteosarcoma cells by suppressing the PI3K/AKT pathway.
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore.
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Rosmarinic Acid as a Candidate in a Phenotypic Profiling Cardio-/Cytotoxicity Cell Model Induced by Doxorubicin.
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota.
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca(2+)-Dependent Antioxidant Response.
Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9.
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Man S, Bi J, Liu F, Xie W, Ma L
Molecular nutrition & food research 2024 Mar;68(6):e2300706
Molecular nutrition & food research 2024 Mar;68(6):e2300706
Targeting autophagy overcomes cancer-intrinsic resistance to CAR-T immunotherapy in B-cell malignancies.
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Cancer communications (London, England) 2024 Mar;44(3):408-432
Cancer communications (London, England) 2024 Mar;44(3):408-432
Identification and validation of DHCR7 as a diagnostic biomarker involved in the proliferation and mitochondrial function of breast cancer.
Wang Y, Fan J, Liu Y, Du J, Liang B, Wang H, Song Z
Aging 2024 Mar 22;16(7):5967-5986
Aging 2024 Mar 22;16(7):5967-5986
GL-V9 inhibits the activation of AR-AKT-HK2 signaling networks and induces prostate cancer cell apoptosis through mitochondria-mediated mechanism.
Wang R, Min Q, Guo Y, Zhou Y, Zhang X, Wang D, Gao Y, Wei L
iScience 2024 Mar 15;27(3):109246
iScience 2024 Mar 15;27(3):109246
Echinacoside alleviates glucocorticoid induce osteonecrosis of femoral head in rats through PI3K/AKT/FOXO1 pathway.
Huang LK, Zeng XS, Jiang ZW, Peng H, Sun F
Chemico-biological interactions 2024 Mar 1;391:110893
Chemico-biological interactions 2024 Mar 1;391:110893
ZNF862 induces cytostasis and apoptosis via the p21-RB1 and Bcl-xL-Caspase 3 signaling pathways in human gingival fibroblasts.
Zhu Y, Zhao T, Wu Y, Xie S, Sun W, Wu J
Journal of periodontal research 2024 Jun;59(3):599-610
Journal of periodontal research 2024 Jun;59(3):599-610
Reactive Oxygen Species-Mediated Mitophagy and Cell Apoptosis are Involved in the Toxicity of Aluminum Chloride Exposure in GC-2spd.
Peng HX, Chai F, Chen KH, Huang YX, Wei GJ, Yuan H, Pang YF, Luo SH, Wang CF, Chen WC
Biological trace element research 2024 Jun;202(6):2616-2629
Biological trace element research 2024 Jun;202(6):2616-2629
Mammalian orthoreovirus capsid protein σ3 antagonizes RLR-mediated antiviral responses by degrading MAVS.
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mSphere 2024 Jun 25;9(6):e0023624
mSphere 2024 Jun 25;9(6):e0023624
3'-Hydroxypterostilbene Potently Suppresses Tumor Growth via Inhibiting the Activation of the JAK2/STAT3 Pathway in Ovarian Clear Cell Carcinoma.
Koh YC, Huang WZ, Nagabhushanam K, Ho CT, Pan MH
Molecular nutrition & food research 2024 Jan;68(1):e2300108
Molecular nutrition & food research 2024 Jan;68(1):e2300108
Sanguinarine chloride induces ferroptosis by regulating ROS/BACH1/HMOX1 signaling pathway in prostate cancer.
Liu S, Tao Y, Wu S, Lin J, Fu S, Lu J, Zhang J, Fu B, Zhang E, Xu J, Wang J, Li L, Zhang L, Wang Z
Chinese medicine 2024 Jan 9;19(1):7
Chinese medicine 2024 Jan 9;19(1):7
Stress granules affect the dual PI3K/mTOR inhibitor response by regulating the mitochondrial unfolded protein response.
Lin N, Sun L, Chai J, Qi H, Zhao Y, Ma J, Xia M, Hu X
Cancer cell international 2024 Jan 18;24(1):38
Cancer cell international 2024 Jan 18;24(1):38
A study on the role of Taxifolin in inducing apoptosis of pancreatic cancer cells: screening results using weighted gene co-expression network analysis.
Chen SJ, Ren LK, Fei XB, Liu P, Wang X, Zhu CH, Pan YZ
Aging 2024 Feb 1;16(3):2617-2637
Aging 2024 Feb 1;16(3):2617-2637
Treadmill training improves lung function and inhibits alveolar cell apoptosis in spinal cord injured rats.
Wang X, Fu Y, Yang X, Chen Y, Zeng N, Hu S, Ouyang S, Pan X, Wu S
Scientific reports 2024 Apr 27;14(1):9723
Scientific reports 2024 Apr 27;14(1):9723
Establishment of sheep nasal mucosa explant model and its application in antiviral research.
Zheng J, Lin J, Ma Y, Yang C, Zhong Q, Li Y, Yang Q
Frontiers in microbiology 2023;14:1124936
Frontiers in microbiology 2023;14:1124936
Crebanine induces ROS-dependent apoptosis in human hepatocellular carcinoma cells via the AKT/FoxO3a signaling pathway.
Tan J, Xiang Y, Xiong Y, Zhang Y, Qiao B, Zhang H
Frontiers in pharmacology 2023;14:1069093
Frontiers in pharmacology 2023;14:1069093
Targeting HSP90 with picropodophyllin suppresses gastric cancer tumorigenesis by disrupting the association of HSP90 and AKT.
Li X, Wang G, Zhou X, Zhao H, Chen X, Cui Q, Li M, Gao X, Wei X, Ye L, Li D, Hong P
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Phytotherapy research : PTR 2023 Oct;37(10):4740-4754
PKM2/PDK1 dual-targeted shikonin derivatives restore the sensitivity of EGFR-mutated NSCLC cells to gefitinib by remodeling glucose metabolism.
Lin H, Han H, Yang M, Wen Z, Chen Q, Ma Y, Wang X, Wang C, Yin T, Wang X, Lu G, Chen H, Qi J, Yang Y
European journal of medicinal chemistry 2023 Mar 5;249:115166
European journal of medicinal chemistry 2023 Mar 5;249:115166
CPT1A modulates PI3K/Akt/mTOR pathway to promote preeclampsia.
Chen M, Chao B, Xu J, Liu Z, Tao Y, He J, Wang J, Yang H, Luo X, Qi H
Placenta 2023 Mar 3;133:23-31
Placenta 2023 Mar 3;133:23-31
An integrated approach of network pharmacology, molecular docking, and experimental verification uncovers kaempferol as the effective modulator of HSD17B1 for treatment of endometrial cancer.
Ruan GY, Ye LX, Lin JS, Lin HY, Yu LR, Wang CY, Mao XD, Zhang SH, Sun PM
Journal of translational medicine 2023 Mar 17;21(1):204
Journal of translational medicine 2023 Mar 17;21(1):204
Chlorogenic Acid Alleviates Hepatic Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress, Inflammation, and Mitochondria-Mediated Apoptosis In Vivo and In Vitro.
Li K, Feng Z, Wang L, Ma X, Wang L, Liu K, Geng X, Peng C
Inflammation 2023 Jun;46(3):1061-1076
Inflammation 2023 Jun;46(3):1061-1076
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway.
Song QQ, Lin LP, Chen YL, Qian JC, Wei K, Su JW, Ding JH, Lu M, Liu Y, Tan RX, Hu G
Acta pharmacologica Sinica 2023 Jun;44(6):1262-1276
Acta pharmacologica Sinica 2023 Jun;44(6):1262-1276
GSDMD knockdown exacerbates hippocampal damage and seizure susceptibility by crosstalk between pyroptosis and apoptosis in kainic acid-induced temporal lobe epilepsy.
Lin A, Guo Y, Zhang H, Lin P, Tao K, Jiang L, Xu D, Chen B
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Biochimica et biophysica acta. Molecular basis of disease 2023 Jun;1869(5):166687
DON entry into the nucleus induces DNA damage, apoptosis and cycle arrest in GES-1 cells.
Hou S, Cheng Y, Wang Z, Xia L, Wang J, Wang H, Sun J, Ma J, Yan Y
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113531
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Jan;171:113531
The protective mechanism of a novel polysaccharide from Lactobacillus-fermented Nostoc commune Vauch. on attenuating cadmium-induced kidney injury in mice.
Li H, Liu Y, Zhou J, Liu S, Liu Y, Yang Y, Wang W, Che Y, Inam M, Guan L
International journal of biological macromolecules 2023 Jan 31;226:1444-1454
International journal of biological macromolecules 2023 Jan 31;226:1444-1454
Simple Nano-Luciferase-Based Assay for the Rapid and High-Throughput Detection of SARS-CoV-2 3C-Like Protease.
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Analytical chemistry 2023 Jan 17;95(2):714-719
Analytical chemistry 2023 Jan 17;95(2):714-719
PM2.5 exposure exacerbates mice thoracic aortic aneurysm and dissection by inducing smooth muscle cell apoptosis via the MAPK pathway.
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Chemosphere 2023 Feb;313:137500
Chemosphere 2023 Feb;313:137500
MitomiR-504 alleviates the copper-induced mitochondria-mediated apoptosis by suppressing Bak1 expression in porcine jejunal epithelial cells.
Hu Z, Linn N, Li Q, Zhang K, Liao J, Han Q, Zhang H, Guo J, Hu L, Pan J, Li Y, Tang Z
The Science of the total environment 2023 Feb 1;858(Pt 3):160157
The Science of the total environment 2023 Feb 1;858(Pt 3):160157
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer.
Zhai L, Yang X, Cheng Y, Wang J
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Cancer medicine 2023 Aug;12(15):16337-16358
Protective Roles of Xijiao Dihuang Tang on Coronary Artery Injury in Kawasaki Disease.
Zhang J, Zhuge Y, Rong X, Ni C, Niu C, Wen Z, Lin H, Chu M, Jia C
Cardiovascular drugs and therapy 2023 Apr;37(2):257-270
Cardiovascular drugs and therapy 2023 Apr;37(2):257-270
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
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Drug design, development and therapy 2022;16:1713-1729
Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway.
Qu XQ, Chen QF, Shi QQ, Luo QQ, Zheng SY, Li YH, Bai LY, Gan S, Zhou XY
Frontiers in immunology 2022;13:901566
Frontiers in immunology 2022;13:901566
Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma.
Li Y, Deng Y, Zhang X, Fu H, Han X, Guo W, Zhao W, Zhao X, Yu C, Li H, Lei K, Wang T
Frontiers in pharmacology 2022;13:897465
Frontiers in pharmacology 2022;13:897465
Integrated network pharmacology and serum metabolomics approach deciphers the anti-colon cancer mechanisms of Huangqi Guizhi Wuwu Decoction.
Pan B, Xia Y, Fang S, Ai J, Wang K, Zhang J, Du C, Chen Y, Liu L, Yan S
Frontiers in pharmacology 2022;13:1043252
Frontiers in pharmacology 2022;13:1043252
Cryptotanshinone protects skin cells from ultraviolet radiation-induced photoaging via its antioxidant effect and by reducing mitochondrial dysfunction and inhibiting apoptosis.
Guo K, Liu R, Jing R, Wang L, Li X, Zhang K, Fu M, Ye J, Hu Z, Zhao W, Xu N
Frontiers in pharmacology 2022;13:1036013
Frontiers in pharmacology 2022;13:1036013
Glucocorticoids induce osteonecrosis of the femoral head in rats via PI3K/AKT/FOXO1 signaling pathway.
Sun F, Zhou JL, Wei SX, Jiang ZW, Peng H
PeerJ 2022;10:e13319
PeerJ 2022;10:e13319
Matrix metalloproteinase-7 promotes chronic kidney disease progression via the induction of inflammasomes and the suppression of autophagy.
Zheng CM, Lu KC, Chen YJ, Li CY, Lee YH, Chiu HW
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113565
RhFGF21 Protects Epidermal Cells against UVB-Induced Apoptosis through Activating AMPK-Mediated Autophagy.
Zhao Y, Lin J, Li J, Bwalya C, Xu Y, Niu Y, Zhang Y, Wu J, Xu Y, Chen J, Ye S, Lin L
International journal of molecular sciences 2022 Oct 18;23(20)
International journal of molecular sciences 2022 Oct 18;23(20)
Kaempferol prevents angiogenesis of rat intestinal microvascular endothelial cells induced by LPS and TNF-α via inhibiting VEGF/Akt/p38 signaling pathways and maintaining gut-vascular barrier integrity.
Yu R, Zhong J, Zhou Q, Ren W, Liu Z, Bian Y
Chemico-biological interactions 2022 Oct 1;366:110135
Chemico-biological interactions 2022 Oct 1;366:110135
Chemical Composition, Antitumor Properties, and Mechanism of the Essential Oil from Plagiomnium acutum T. Kop.
Li M, Wang L, Li S, Hua C, Gao H, Ning D, Li C, Zhang C, Jiang F
International journal of molecular sciences 2022 Nov 26;23(23)
International journal of molecular sciences 2022 Nov 26;23(23)
Ginsenoside Rd ameliorates high glucose-induced retinal endothelial injury through AMPK-STRT1 interdependence.
Tang K, Qin W, Wei R, Jiang Y, Fan L, Wang Z, Tan N
Pharmacological research 2022 May;179:106123
Pharmacological research 2022 May;179:106123
Protective Effect of Resveratrol on Immortalized Duck Intestinal Epithelial Cells Exposed to H(2)O(2).
Zhou N, Tian Y, Wu H, Cao Y, Li R, Zou K, Xu W, Lu L
Molecules (Basel, Switzerland) 2022 May 31;27(11)
Molecules (Basel, Switzerland) 2022 May 31;27(11)
Hernandezine Regulates Proliferation and Autophagy-Induced Apoptosis in Melanoma Cells.
Wang X, Li X, Xia Y, Wang D, Li X, Liu L, Zheng Q, Li D, Jiang Q
Journal of natural products 2022 May 27;85(5):1351-1362
Journal of natural products 2022 May 27;85(5):1351-1362
Role of Nrf2 Nucleus Translocation in Beauvericin-Induced Cell Damage in Rat Hepatocytes.
Shi J, Wang Y, Xu W, Cai G, Zou H, Yuan Y, Gu J, Liu Z, Bian J
Toxins 2022 May 25;14(6)
Toxins 2022 May 25;14(6)
Mechanism of a new photosensitizer (TBZPy) in the treatment of high-risk human papillomavirus-related diseases.
Li Z, Xiao Z, Feng Y, Wang Q, Teng M
Photodiagnosis and photodynamic therapy 2022 Mar;37:102591
Photodiagnosis and photodynamic therapy 2022 Mar;37:102591
Enhanced photodynamic therapy/photothermo therapy for nasopharyngeal carcinoma via a tumour microenvironment-responsive self-oxygenated drug delivery system.
Wu N, Tu Y, Fan G, Ding J, Luo J, Wang W, Zhang C, Yuan C, Zhang H, Chen P, Tan S, Xiao H
Asian journal of pharmaceutical sciences 2022 Mar;17(2):253-267
Asian journal of pharmaceutical sciences 2022 Mar;17(2):253-267
Chlorine disinfection elevates the toxicity of polystyrene microplastics to human cells by inducing mitochondria-dependent apoptosis.
Qin J, Xia PF, Yuan XZ, Wang SG
Journal of hazardous materials 2022 Mar 5;425:127842
Journal of hazardous materials 2022 Mar 5;425:127842
Protection of pancreatic β-cell by phosphocreatine through mitochondrial improvement via the regulation of dual AKT/IRS-1/GSK-3β and STAT3/Cyp-D signaling pathways.
Wang H, Ai J, Shopit A, Niu M, Ahmed N, Tesfaldet T, Tang Z, Li X, Jamalat Y, Chu P, Peng J, Ma X, Qaed E, Han G, Zhang W, Wang J, Tang Z
Cell biology and toxicology 2022 Jun;38(3):531-551
Cell biology and toxicology 2022 Jun;38(3):531-551
The role of ER stress and ATP/AMPK in oxidative stress meditated hepatotoxicity induced by citrinin.
Wu J, Yang C, Yang M, Liang Z, Wu Y, Kong X, Fan H, Wang S, Ning C, Xiao W, Jin Y, Yi J, Yuan Z
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
Ecotoxicology and environmental safety 2022 Jun 1;237:113531
LS-HB-Mediated Photodynamic Therapy Inhibits Proliferation and Induces Cell Apoptosis in Melanoma.
Wang L, Wang L, Zhang Y, Zhao Z, Liu C, Li M, Liu J, Wang S, Yang D, Luo F, Yan J
Molecular pharmaceutics 2022 Jul 4;19(7):2607-2619
Molecular pharmaceutics 2022 Jul 4;19(7):2607-2619
MBD1/HDAC3-miR-5701-FGFR2 axis promotes the development of gastric cancer.
Zhao C, Miao J, Sun R, Liang R, Chen W, Gao Y, Wang X, Han S, Zhao W, Lei T, Huang C
Aging 2022 Jul 22;14(14):5878-5894
Aging 2022 Jul 22;14(14):5878-5894
Alnustone inhibits the growth of hepatocellular carcinoma via ROS- mediated PI3K/Akt/mTOR/p70S6K axis.
Wang L, Cheng L, Ma L, Ahmad Farooqi A, Qiao G, Zhang Y, Ye H, Liu M, Huang J, Yang X, Lin X, Cao S
Phytotherapy research : PTR 2022 Jan;36(1):525-542
Phytotherapy research : PTR 2022 Jan;36(1):525-542
OLFM4 depletion sensitizes gallbladder cancer cells to cisplatin through the ARL6IP1/caspase-3 axis.
Lin Z, Yang S, Zhou Y, Hou Z, Li L, Meng M, Ge C, Zeng B, Lai J, Gao H, Zhao Y, Xie Y, He S, Tang W, Li R, Tan J, Wang W
Translational oncology 2022 Feb;16:101331
Translational oncology 2022 Feb;16:101331
Design, synthesis and biological evaluation of novel 1,3,4,9-tetrahydropyrano[3,4-b]indoles as potential treatment of triple negative breast cancer by suppressing PI3K/AKT/mTOR pathway.
Qin J, Sun X, Ma Y, Cheng Y, Ma Q, Jing W, Qu S, Liu L
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Bioorganic & medicinal chemistry 2022 Feb 1;55:116594
Danggui Niantong granules ameliorate rheumatoid arthritis by regulating intestinal flora and promoting mitochondrial apoptosis.
Lu QJ, Li JY, Lin HX, Cai YS, Liu CS, Fu LP, Liu G, Yuan LX
Pharmaceutical biology 2022 Dec;60(1):1606-1615
Pharmaceutical biology 2022 Dec;60(1):1606-1615
Mecheliolide elicits ROS-mediated ERS driven immunogenic cell death in hepatocellular carcinoma.
Xu Z, Xu J, Sun S, Lin W, Li Y, Lu Q, Li F, Yang Z, Lu Y, Liu W
Redox biology 2022 Aug;54:102351
Redox biology 2022 Aug;54:102351
Lianhuaqingwen alleviates p53-mediated apoptosis in alveolar epithelial cells to prevent LPS-induced ALI.
Yang R, Yang H, Li W, Yue F, Chen H, Hao Y, Hu K
The Journal of pharmacy and pharmacology 2022 Aug 19;74(8):1117-1124
The Journal of pharmacy and pharmacology 2022 Aug 19;74(8):1117-1124
Hydroxysafflor yellow A acutely attenuates blood-brain barrier permeability, oxidative stress, inflammation and apoptosis in traumatic brain injury in rats1.
Xu J, Zhan T, Zheng W, Huang YK, Chen K, Zhang XH, Ren P, Huang X
Acta cirurgica brasileira 2021;35(12):e351202
Acta cirurgica brasileira 2021;35(12):e351202
Farrerol Enhances Nrf2-Mediated Defense Mechanisms against Hydrogen Peroxide-Induced Oxidative Damage in Human Retinal Pigment Epithelial Cells by Activating Akt and MAPK.
Ma N, Yang X, Qi C, Yu Q, Zhu C, Ren H
Oxidative medicine and cellular longevity 2021;2021:8847844
Oxidative medicine and cellular longevity 2021;2021:8847844
Lenvatinib induces anticancer activity in gallbladder cancer by targeting AKT.
Ye J, Qi L, Liang J, Zong K, Liu W, Li R, Feng R, Zhai W
Journal of Cancer 2021;12(12):3548-3557
Journal of Cancer 2021;12(12):3548-3557
Sonodynamic Effects of a Novel Ether-Group Modified Porphyrin Derivative Combined With Pulsed Low-Intensity Ultrasound on PC-9 Cells.
Jin Y, Zhou Q, Geng J, Meng Q, Wei Z, Ding M, Zhou J, Zeng Y, Cao W, Liu F, Yu Y
Frontiers in pharmacology 2021;12:792360
Frontiers in pharmacology 2021;12:792360
Mechanisms Underlying the Effects of Lianhua Qingwen on Sepsis-Induced Acute Lung Injury: A Network Pharmacology Approach.
Yang R, Yang H, Wei J, Li W, Yue F, Song Y, He X, Hu K
Frontiers in pharmacology 2021;12:717652
Frontiers in pharmacology 2021;12:717652
Astragalin Inhibits the Proliferation and Migration of Human Colon Cancer HCT116 Cells by Regulating the NF-κB Signaling Pathway.
Yang M, Li WY, Xie J, Wang ZL, Wen YL, Zhao CC, Tao L, Li LF, Tian Y, Sheng J
Frontiers in pharmacology 2021;12:639256
Frontiers in pharmacology 2021;12:639256
A Potential Mechanism Underlying the Therapeutic Effects of Progesterone and Allopregnanolone on Ketamine-Induced Cognitive Deficits.
Cao T, Tang M, Jiang P, Zhang B, Wu X, Chen Q, Zeng C, Li N, Zhang S, Cai H
Frontiers in pharmacology 2021;12:612083
Frontiers in pharmacology 2021;12:612083
m(6)A-mediated upregulation of AC008 promotes osteoarthritis progression through the miR-328-3p‒AQP1/ANKH axis.
Yang J, Zhang M, Yang D, Ma Y, Tang Y, Xing M, Li L, Chen L, Jin Y, Ma C
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Experimental & molecular medicine 2021 Nov;53(11):1723-1734
Oxidative stress-mediated apoptosis is involved in bisphenol S-induced reproductive toxicity in male C57BL/6 mice.
Dai W, He QZ, Zhu BQ, Zeng HC
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
Journal of applied toxicology : JAT 2021 Nov;41(11):1839-1851
The inhibitory effect Polygonum Cillinerve polysaccharide on transmissible gastroenteritis virus of swine.
Pan X, Zhou Y, Duan X, Cui J, Liu J, Song X, Ma W, Zhang W, Liu Y, Fan Y
Research in veterinary science 2021 Nov;140:47-55
Research in veterinary science 2021 Nov;140:47-55
Autophagy Induction by Trichodermic Acid Attenuates Endoplasmic Reticulum Stress-Mediated Apoptosis in Colon Cancer Cells.
Qu J, Zeng C, Zou T, Chen X, Yang X, Lin Z
International journal of molecular sciences 2021 May 25;22(11)
International journal of molecular sciences 2021 May 25;22(11)
Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism.
Pan H, Xu Y, Cai Q, Wu M, Ding M
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
Medical science monitor : international medical journal of experimental and clinical research 2021 Jun 4;27:e931884
BAIAP2L2 promotes the proliferation, migration and invasion of osteosarcoma associated with the Wnt/β-catenin pathway.
Guo H, Peng J, Hu J, Chang S, Liu H, Luo H, Chen X, Tang H, Chen Y
Journal of bone oncology 2021 Dec;31:100393
Journal of bone oncology 2021 Dec;31:100393
Protective effect of Idelalisib on carbon tetrachloride-induced liver fibrosis via microRNA-124-3P/phosphatidylinositol-3-hydroxykinase signalling pathway.
Li X, Li H, Zhang S, Zhang R, Li J, Wei Y, Yang C, Zhang F, Zhou H
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
Journal of cellular and molecular medicine 2021 Dec;25(24):11185-11197
Integration of exonuclease III-powered three-dimensional DNA walker with single-molecule detection for multiple initiator caspases assay.
Liu M, Xu R, Liu W, Qiu JG, Wang Y, Ma F, Zhang CY
Chemical science 2021 Dec 8;12(47):15645-15654
Chemical science 2021 Dec 8;12(47):15645-15654
A Natural Degradant of Curcumin, Feruloylacetone Inhibits Cell Proliferation via Inducing Cell Cycle Arrest and a Mitochondrial Apoptotic Pathway in HCT116 Colon Cancer Cells.
Chou YT, Koh YC, Nagabhushanam K, Ho CT, Pan MH
Molecules (Basel, Switzerland) 2021 Aug 12;26(16)
Molecules (Basel, Switzerland) 2021 Aug 12;26(16)
Limonin induces apoptosis of HL-60 cells by inhibiting NQO1 activity.
Chen Y, Liang J, Liang X, Chen J, Wang Y, Cao J, Sun C, Ye J, Chen Q
Food science & nutrition 2021 Apr;9(4):1860-1869
Food science & nutrition 2021 Apr;9(4):1860-1869
Niclosamide: drug repurposing for human chondrosarcoma treatment via the caspase-dependent mitochondrial apoptotic pathway.
Yu QS, Xin HR, Qiu RL, Deng ZL, Deng F, Yan ZJ
American journal of translational research 2020;12(7):3688-3701
American journal of translational research 2020;12(7):3688-3701
Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53.
Almoiliqy M, Wen J, Xu B, Sun YC, Lian MQ, Li YL, Qaed E, Al-Azab M, Chen DP, Shopit A, Wang L, Sun PY, Lin Y
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Acta pharmacologica Sinica 2020 Sep;41(9):1208-1222
Proanthocyanidin B2 inhibits proliferation and induces apoptosis of osteosarcoma cells by suppressing the PI3K/AKT pathway.
Wu X, Yu H, Zhou H, Li Z, Huang H, Xiao F, Xu S, Yang Y
Journal of cellular and molecular medicine 2020 Oct;24(20):11960-11971
Journal of cellular and molecular medicine 2020 Oct;24(20):11960-11971
HIF-1α ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics.
Jiang N, Zhao H, Han Y, Li L, Xiong S, Zeng L, Xiao Y, Wei L, Xiong X, Gao P, Yang M, Liu Y, Sun L
Cell proliferation 2020 Nov;53(11):e12909
Cell proliferation 2020 Nov;53(11):e12909
Curculigoside attenuates myocardial ischemia‑reperfusion injury by inhibiting the opening of the mitochondrial permeability transition pore.
Zhao Y, Guo Y, Chen Y, Liu S, Wu N, Jia D
International journal of molecular medicine 2020 May;45(5):1514-1524
International journal of molecular medicine 2020 May;45(5):1514-1524
Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway.
Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, Li S, Zhang J, Dai W, Xu X, Mao Y, Xu S, Chen K, Li J, Guo C
International immunopharmacology 2020 Jul;84:106529
International immunopharmacology 2020 Jul;84:106529
Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy.
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, Quan C, Yao Y, Zheng Z
BMC cancer 2020 Jul 16;20(1):665
BMC cancer 2020 Jul 16;20(1):665
Rosmarinic Acid as a Candidate in a Phenotypic Profiling Cardio-/Cytotoxicity Cell Model Induced by Doxorubicin.
Zhang Q, Li J, Peng S, Zhang Y, Qiao Y
Molecules (Basel, Switzerland) 2020 Feb 14;25(4)
Molecules (Basel, Switzerland) 2020 Feb 14;25(4)
Pseudolaric acid B induces apoptosis in human rhabdomyosarcoma RD cells.
Liu C, Wang F, Wang B, Wu T, Wang Y, Huo W, Zhang S, Su Y, Liu J, Liu Y, Yu J
Oncology letters 2020 Dec;20(6):358
Oncology letters 2020 Dec;20(6):358
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Wu L, Mo W, Feng J, Li J, Yu Q, Li S, Zhang J, Chen K, Ji J, Dai W, Wu J, Xu X, Mao Y, Guo C
British journal of pharmacology 2020 Aug;177(16):3760-3777
British journal of pharmacology 2020 Aug;177(16):3760-3777
Leukemia cells apoptosis by a newly discovered heterogeneous polysaccharide from Angelica sinensis (Oliv.) Diels.
Liu W, Xiao K, Ren L, Sui Y, Chen J, Zhang T, Li XQ, Cao W
Carbohydrate polymers 2020 Aug 1;241:116279
Carbohydrate polymers 2020 Aug 1;241:116279
Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer.
Bai L, Liang J, Li L, Li E
Oncology reports 2020 Apr;43(4):1208-1220
Oncology reports 2020 Apr;43(4):1208-1220
Caspase-8 Induces Lysosome-Associated Cell Death in Cancer Cells.
Zhong B, Liu M, Bai C, Ruan Y, Wang Y, Qiu L, Hong Y, Wang X, Li L, Li B
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Apr 8;28(4):1078-1091
Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer.
Liao X, Fan Y, Hou J, Chen X, Xu X, Yang Y, Shen J, Mi P, Huang X, Zhang W, Cao H, Hong X, Hu T, Zhan YY
Journal of Cancer 2019;10(16):3678-3690
Journal of Cancer 2019;10(16):3678-3690
Viral Nonstructural Protein 1 Induces Mitochondrion-Mediated Apoptosis in Mink Enteritis Virus Infection.
Lin P, Cheng Y, Song S, Qiu J, Yi L, Cao Z, Li J, Cheng S, Wang J
Journal of virology 2019 Nov 15;93(22)
Journal of virology 2019 Nov 15;93(22)
Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury.
Mo D, Tian W, Zhang HN, Feng YD, Sun Y, Quan W, Hao XW, Wang XY, Liu XX, Li C, Cao W, Liu WJ, Li XQ
European journal of pharmacology 2019 Nov 15;863:172701
European journal of pharmacology 2019 Nov 15;863:172701
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma.
Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, Chen J, Mao Y, Wang F, Dai W, Xu L, Wu J, Guo C
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Journal of experimental & clinical cancer research : CR 2019 May 17;38(1):204
Restoration of p53 acetylation by HDAC inhibition permits the necrosis/apoptosis switch of pancreatic ainar cell during experimental pancreatitis in mice.
Hu Y, Dai J, Zong G, Xiao J, Guo X, Dai Y, Lu Z, Wan R
Journal of cellular physiology 2019 Dec;234(12):21988-21998
Journal of cellular physiology 2019 Dec;234(12):21988-21998
KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma.
Li SS, Jiang WL, Xiao WQ, Li K, Zhang YF, Guo XY, Dai YQ, Zhao QY, Jiang MJ, Lu ZJ, Wan R
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
World journal of gastrointestinal oncology 2019 Aug 15;11(8):599-621
Cell Cycle Arrest and Apoptosis in HT-29 Cells Induced by Dichloromethane Fraction From Toddalia asiatica (L.) Lam.
Li X, Qiu Z, Jin Q, Chen G, Guo M
Frontiers in pharmacology 2018;9:629
Frontiers in pharmacology 2018;9:629
Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway.
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, Zhang J, Ma W, Zhou D, Li X, Ye X
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Journal of agricultural and food chemistry 2018 Sep 19;66(37):9704-9718
Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota.
Ren W, Wang P, Yan J, Liu G, Zeng B, Hussain T, Peng C, Yin J, Li T, Wei H, Zhu G, Reiter RJ, Tan B, Yin Y
Journal of pineal research 2018 Mar;64(2)
Journal of pineal research 2018 Mar;64(2)
Pseudo-Ginsenoside Rh2 induces A549 cells apoptosis via the Ras/Raf/ERK/p53 pathway.
Wang Y, Xu H, Lu Z, Yu X, Lv C, Tian Y, Sui D
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Experimental and therapeutic medicine 2018 Jun;15(6):4916-4924
Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury.
Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, Li J, Li S, Wang W, Lu X, Yu Q, Liu N, Xu L, Wang F, Dai W, Xia Y, Fan X, Guo C
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
Experimental and therapeutic medicine 2018 Jun;15(6):4599-4614
A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells.
Fu W, Li X, Lu X, Zhang L, Li R, Zhang N, Liu S, Yang X, Wang Y, Zhao Y, Meng X, Zhu WG
Cell death & disease 2017 Oct 5;8(10):e3086
Cell death & disease 2017 Oct 5;8(10):e3086
MICU1 Alleviates Diabetic Cardiomyopathy Through Mitochondrial Ca(2+)-Dependent Antioxidant Response.
Ji L, Liu F, Jing Z, Huang Q, Zhao Y, Cao H, Li J, Yin C, Xing J, Li F
Diabetes 2017 Jun;66(6):1586-1600
Diabetes 2017 Jun;66(6):1586-1600
Active site-adjacent phosphorylation at Tyr-397 by c-Abl kinase inactivates caspase-9.
Serrano BP, Szydlo HS, Alfandari D, Hardy JA
The Journal of biological chemistry 2017 Dec 29;292(52):21352-21365
The Journal of biological chemistry 2017 Dec 29;292(52):21352-21365
Increased mitochondrial fission promotes autophagy and hepatocellular carcinoma cell survival through the ROS-modulated coordinated regulation of the NFKB and TP53 pathways.
Huang Q, Zhan L, Cao H, Li J, Lyu Y, Guo X, Zhang J, Ji L, Ren T, An J, Liu B, Nie Y, Xing J
Autophagy 2016 Jun 2;12(6):999-1014
Autophagy 2016 Jun 2;12(6):999-1014
Gliotoxin Inhibits Proliferation and Induces Apoptosis in Colorectal Cancer Cells.
Chen J, Wang C, Lan W, Huang C, Lin M, Wang Z, Liang W, Iwamoto A, Yang X, Liu H
Marine drugs 2015 Oct 2;13(10):6259-73
Marine drugs 2015 Oct 2;13(10):6259-73
Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells.
Hu L, Su C, Song X, Shi Q, Fu J, Xia X, Xu D, Song E, Song Y
Neurotoxicology 2015 Jul;49:149-57
Neurotoxicology 2015 Jul;49:149-57
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 66169-1-Ig( Caspase 9 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Caspase 9 antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human Caspase 9. This antibody recognizes human antigen. The Caspase 9 antibody has been validated for the following applications: ELISA, WB, IHC analysis.