CASP9

gene product
APAF-3, ICE-LAP6, MCH6, PPP1R56
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
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antibodies-online
635 antibodies
Novus Biologicals
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GeneTex
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NovoPro Bioscience Inc.
8 antibodies
Invitrogen Antibodies
24 antibodies
Abnova Corporation
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Proteintech Group
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Boster Biological Technology
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LifeSpan BioSciences, Inc.
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Biorbyt
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R&D Systems
2 antibodies
Aviva Systems Biology
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Acris Antibodies GmbH
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Santa Cruz Biotechnology
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Affinity Biosciences
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OriGene
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Cell Signaling Technology, Inc
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St John's Laboratory
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Abgent
18 antibodies
NSJ Bioreagents
4 antibodies
Atlas Antibodies
2 antibodies
Bioworld Technology, Inc
10 antibodies
Arigo
6 antibodies
Abbexa
3 antibodies
BioLegend
2 antibodies
Rockland Immunochemicals, Inc.
2 antibodies
ProSci
6 antibodies
RabMAbs
8 antibodies
Abbkine Scientific Co.Ltd.
12 antibodies
Signalway Antibody LLC
2 antibodies
Bethyl Laboratories
1 antibody
Creative Biolabs
47 antibodies
MyBioSource
29 antibodies
Abbiotec
5 antibodies
United States Biological
167 antibodies
RayBiotech, Inc.
5 antibodies
EMD Millipore
5 antibodies
Creative Diagnostics
12 antibodies
GenWay
16 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Sigma-Aldrich
5 antibodies
Exalpha Biologicals, Inc.
4 antibodies
Active Motif
1 antibody