Tissue expression
Cell line expression

CASP9

gene product
APAF-3, ICE-LAP6, MCH6, PPP1R56 
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
More gene data

Antibodies

 

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2248 antibodies from 50 providers.

Antibody properties

Applications

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AntibodyRefsTypeWBELICCIPIHCFC
Proteintech Group
9 antibodies
Invitrogen Antibodies
91 antibodies
antibodies-online
635 antibodies
Novus Biologicals
17 antibodies
Biorbyt
431 antibodies
GeneTex
17 antibodies
NovoPro Bioscience Inc.
8 antibodies
Wuhan Fine Biotech Co., Ltd.
5 antibodies
Abnova Corporation
28 antibodies
Boster Biological Technology
19 antibodies
Enzo Life Sciences
12 antibodies
OriGene
41 antibodies
LifeSpan BioSciences, Inc.
272 antibodies
St John's Laboratory
21 antibodies
R&D Systems
2 antibodies
Aviva Systems Biology
16 antibodies
Acris Antibodies GmbH
47 antibodies
Santa Cruz Biotechnology
1 antibody
Cusabio Biotech Co., Ltd
23 antibodies
Affinity Biosciences
6 antibodies
Cell Signaling Technology, Inc
12 antibodies
NSJ Bioreagents
5 antibodies
Abgent
18 antibodies
HUABIO Research
4 antibodies
Atlas Antibodies
2 antibodies
Bioworld Technology, Inc
10 antibodies
Arigo
6 antibodies
BioLegend
2 antibodies
ProSci
6 antibodies
RabMAbs
8 antibodies
Abbkine Scientific Co.Ltd.
12 antibodies
Signalway Antibody LLC
2 antibodies
Bethyl Laboratories
1 antibody
Creative Biolabs
51 antibodies
Abbexa
35 antibodies
MyBioSource
29 antibodies
Abbiotec
5 antibodies
MilliporeSigma / Merck KGaA
9 antibodies
United States Biological
167 antibodies
RayBiotech, Inc.
5 antibodies
Leading Biology
11 antibodies
EMD Millipore
5 antibodies
QED Bioscience
2 antibodies
Creative Diagnostics
12 antibodies
GenWay
16 antibodies
eBioscience, An Affymetrix Company
2 antibodies
Exalpha Biologicals, Inc.
4 antibodies
Active Motif
1 antibody
Rockland Immunochemicals, Inc.
2 antibodies