Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BMS1041 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Caspase 9 Monoclonal Antibody (96-2-2), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: Caspase-9, formerly called Apaf-3, binds to Apaf-1 in the presence of cytochrome c and dATP (3), which leads to caspase-9 activation. Activated caspase-9 in turn cleaves and activates caspase-3; caspase-9 thus is the most upstream member of the apoptotic protease cascade that is triggered by cytochrome c and dATP. Caspase-9 is essentially localized in mitochondria, the disruption of the outer mitochondrial membrane occurring early during apoptosis is critical for its subcellular redistribution and activation. Applications Tested: ELISA, Immunoprecipitation, Western Blotting. Reconstitution instructions: A quick spin is recommended followed by reconstitution in PBS, pH 7.2 to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 96-2-2
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- 4° C
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