Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- ABIN499577 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibody
- Antibody type
- Polyclonal
- Antigen
- Human Caspase-9 (Intermediate Domain 1) Peptide (ABIN499576)
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the antibody undiluted at 2-8°C. Shelf life: one year from despatch.
Submitted references Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex.
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
Pan G, O'Rourke K, Dixit VM
The Journal of biological chemistry 1998 Mar 6;273(10):5841-5
The Journal of biological chemistry 1998 Mar 6;273(10):5841-5
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade.
Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X
Cell 1997 Nov 14;91(4):479-89
Cell 1997 Nov 14;91(4):479-89
The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32.
Srinivasula SM, Fernandes-Alnemri T, Zangrilli J, Robertson N, Armstrong RC, Wang L, Trapani JA, Tomaselli KJ, Litwack G, Alnemri ES
The Journal of biological chemistry 1996 Oct 25;271(43):27099-106
The Journal of biological chemistry 1996 Oct 25;271(43):27099-106
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B.
Duan H, Orth K, Chinnaiyan AM, Poirier GG, Froelich CJ, He WW, Dixit VM
The Journal of biological chemistry 1996 Jul 12;271(28):16720-4
The Journal of biological chemistry 1996 Jul 12;271(28):16720-4
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of caspase-9 in HeLa whole cell lysate with AP30205PU-N caspase-9 antibody at 1/1000 dilution.