Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- PAB7881 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB7881, RRID:AB_1672173
- Product name
- BRAF polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of BRAF .
- Storage
- Store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization.
Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein.
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
Karbowniczek M, Robertson GP, Henske EP
The Journal of biological chemistry 2006 Sep 1;281(35):25447-56
The Journal of biological chemistry 2006 Sep 1;281(35):25447-56
Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein.
Brummer T, Martin P, Herzog S, Misawa Y, Daly RJ, Reth M
Oncogene 2006 Oct 12;25(47):6262-76
Oncogene 2006 Oct 12;25(47):6262-76
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.
Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA
Cancer research 2004 Oct 1;64(19):7099-109
Cancer research 2004 Oct 1;64(19):7099-109
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot of human Jurkat cells treated with calyculin A (100 nM) for 30 min. The blots were untreated (lane 1) or treated (lane 2) with lambda phosphatase and probed with BRAF polyclonal antibody (Cat # PAB7881).