BRAF

gene product
BRAF1
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
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OriGene
80 antibodies
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Novus Biologicals
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antibodies-online
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Arigo
8 antibodies
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4 antibodies
Santa Cruz Biotechnology
1 antibody
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Aviva Systems Biology
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LifeSpan BioSciences, Inc.
232 antibodies