BRAF

gene product
BRAF1
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
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Antibodies

 

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Antibodypedia Validation Initiative

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  or   Clear
Enhanced validation
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1959 antibodies from 45 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
antibodies-online
643 antibodies
OriGene
79 antibodies
GeneTex
24 antibodies
Novus Biologicals
45 antibodies
Biorbyt
116 antibodies