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Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- ELISA [1]
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- Product number
- RA0045 - Provider product page
- Provider
- Oursmab
- Product name
- Empasiprubart (Biosimilar Reference Antibody) (C2)
- Antibody type
- Monoclonal
- Description
- Empasiprubart (development code ARGX-117) is an investigational, humanized monoclonal antibody designed for the treatment of complement-mediated diseases. It functions as a targeted inhibitor of the classical and lectin pathways of the complement system. Unlike inhibitors that target the terminal pathway (e.g., anti-C5) or the alternative pathway amplification loop (e.g., anti-Factor B), empasiprubart specifically binds to and neutralizes complement component C2. By inhibiting C2, the drug prevents the formation of the C3 convertase in both the classical and lectin pathways, thereby blocking these specific activation routes at an early, upstream point while leaving the alternative pathway intact for baseline immune surveillance.
- Reactivity
- Human
- Isotype
- IgG
- Vial size
- 100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
- Concentration
- Bottled at the concentration indicated on the vial.
- Storage
- Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
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Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- Empasiprubart (Biosimilar Reference Antibody) (C2)-RA0045-Oursmab determined by SDS-PAGE. The purity of the protein is greater than 98%.
Supportive validation
- Submitted by
- Oursmab (provider)
- Main image
- Experimental details
- ELISA plate pre-coated Antigen protein, can bind Empasiprubart (Biosimilar Reference Antibody) (C2)-RA0045 in a linear range of 3.91-125 ng/mL.
