RA0045

antibody from Oursmab

Targeting: C2

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0045

Provider

Oursmab

Product name

Empasiprubart (Biosimilar Reference Antibody) (C2)

Antibody type

Monoclonal

Description

Empasiprubart (development code ARGX-117) is an investigational, humanized monoclonal antibody designed for the treatment of complement-mediated diseases. It functions as a targeted inhibitor of the classical and lectin pathways of the complement system. Unlike inhibitors that target the terminal pathway (e.g., anti-C5) or the alternative pathway amplification loop (e.g., anti-Factor B), empasiprubart specifically binds to and neutralizes complement component C2. By inhibiting C2, the drug prevents the formation of the C3 convertase in both the classical and lectin pathways, thereby blocking these specific activation routes at an early, upstream point while leaving the alternative pathway intact for baseline immune surveillance.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.