Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- MAB143-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Human Decorin Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human Decorin in direct ELISAs and Western blots. In direct ELISAs, this antibody does not cross-react with recombinant mouse Decorin.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
NP_598013.1
- Isotype
- IgG
- Antibody clone number
- 115402
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Transcriptome analysis of skin fibroblasts with dominant negative COL3A1 mutations provides molecular insights into the etiopathology of vascular Ehlers-Danlos syndrome.
Dermatan sulfate is a player in the transglutaminase 2 interaction network.
Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy.
Possible dual role of decorin in abdominal aortic aneurysm.
Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta.
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Lack of CXC chemokine receptor 3 signaling leads to hypertrophic and hypercellular scarring.
Role of decorin in the antimyeloma effects of osteoblasts.
Chiarelli N, Carini G, Zoppi N, Ritelli M, Colombi M
PloS one 2018;13(1):e0191220
PloS one 2018;13(1):e0191220
Dermatan sulfate is a player in the transglutaminase 2 interaction network.
Wisowski G, Koźma EM, Bielecki T, Pudełko A, Olczyk K
PloS one 2017;12(2):e0172263
PloS one 2017;12(2):e0172263
Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy.
Martínez-Aguilar J, Clifton-Bligh R, Molloy MP
Scientific reports 2016 Mar 30;6:23660
Scientific reports 2016 Mar 30;6:23660
Possible dual role of decorin in abdominal aortic aneurysm.
Ueda K, Yoshimura K, Yamashita O, Harada T, Morikage N, Hamano K
PloS one 2015;10(3):e0120689
PloS one 2015;10(3):e0120689
Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta.
Syx D, Guillemyn B, Symoens S, Sousa AB, Medeira A, Whiteford M, Hermanns-Lê T, Coucke PJ, De Paepe A, Malfait F
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Aug;30(8):1445-56
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2015 Aug;30(8):1445-56
Faulty initiation of proteoglycan synthesis causes cardiac and joint defects.
Baasanjav S, Al-Gazali L, Hashiguchi T, Mizumoto S, Fischer B, Horn D, Seelow D, Ali BR, Aziz SA, Langer R, Saleh AA, Becker C, Nürnberg G, Cantagrel V, Gleeson JG, Gomez D, Michel JB, Stricker S, Lindner TH, Nürnberg P, Sugahara K, Mundlos S, Hoffmann K
American journal of human genetics 2011 Jul 15;89(1):15-27
American journal of human genetics 2011 Jul 15;89(1):15-27
Lack of CXC chemokine receptor 3 signaling leads to hypertrophic and hypercellular scarring.
Yates CC, Krishna P, Whaley D, Bodnar R, Turner T, Wells A
The American journal of pathology 2010 Apr;176(4):1743-55
The American journal of pathology 2010 Apr;176(4):1743-55
Role of decorin in the antimyeloma effects of osteoblasts.
Li X, Pennisi A, Yaccoby S
Blood 2008 Jul 1;112(1):159-68
Blood 2008 Jul 1;112(1):159-68
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Human Decorin by Western Blot. Western blot shows lysates of human uterus tissue and human heart tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human Decorin Monoclonal Antibody (Catalog # MAB143) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Decorin at approximately 100 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.