Tissue expression
Cell line expression
Protein structure
DCN
DecorinDSPG2, SLRR1B
This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
Top validated antibodies |
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Proteintech Group | 14667-1-AP | 23 references | Polyclonal |
WB
EL
ICC
IHC |
|
Atlas Antibodies | HPA003315 | 4 references | Polyclonal |
WB
IHC |
|
Invitrogen Antibodies | PA5-27370 | 3 references | Polyclonal |
WB
ICC
IP
IHC
OA
|
|
GeneTex | GTX101250 | 4 references | Polyclonal |
WB
ICC
IP
IHC |
|
LSBio | LS-B17014 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider