Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [2]
- Immunohistochemistry [3]
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Validation data
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- Product number
- NBP1-84970 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-84970, RRID:AB_11013461
- Product name
- Rabbit Polyclonal Decorin Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human Decorin antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Divergent expression of liver transforming growth factor superfamily cytokines after successful portoenterostomy in biliary atresia.
Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells.
Decreased decorin expression in the tumor microenvironment.
Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Kerola A, Lohi J, Heikkilä P, Mutanen A, Jalanko H, Pakarinen MP
Surgery 2019 May;165(5):905-911
Surgery 2019 May;165(5):905-911
Lysyl Oxidase Activity Is Required for Ordered Collagen Fibrillogenesis by Tendon Cells.
Herchenhan A, Uhlenbrock F, Eliasson P, Weis M, Eyre D, Kadler KE, Magnusson SP, Kjaer M
The Journal of biological chemistry 2015 Jun 26;290(26):16440-50
The Journal of biological chemistry 2015 Jun 26;290(26):16440-50
Decreased decorin expression in the tumor microenvironment.
Bozoky B, Savchenko A, Guven H, Ponten F, Klein G, Szekely L
Cancer medicine 2014 Jun;3(3):485-91
Cancer medicine 2014 Jun;3(3):485-91
Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA
PloS one 2012;7(8):e42516
PloS one 2012;7(8):e42516
Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.
Cawthorn TR, Moreno JC, Dharsee M, Tran-Thanh D, Ackloo S, Zhu PH, Sardana G, Chen J, Kupchak P, Jacks LM, Miller NA, Youngson BJ, Iakovlev V, Guidos CJ, Vallis KA, Evans KR, McCready D, Leong WL, Done SJ
PloS one 2012;7(2):e30992
PloS one 2012;7(2):e30992
CD99 is a novel prognostic stromal marker in non-small cell lung cancer.
Edlund K, Lindskog C, Saito A, Berglund A, Pontén F, Göransson-Kultima H, Isaksson A, Jirström K, Planck M, Johansson L, Lambe M, Holmberg L, Nyberg F, Ekman S, Bergqvist M, Landelius P, Lamberg K, Botling J, Ostman A, Micke P
International journal of cancer 2012 Nov 15;131(10):2264-73
International journal of cancer 2012 Nov 15;131(10):2264-73
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Decorin Antibody [NBP1-84970] - Analysis in human cell line U-2197.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Decorin Antibody [NBP1-84970] - Analysis in control (vector only transfected HEK293T lysate) and DCN over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining of human cerebral cortex shows low expression as expected.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining of human ovary shows high expression.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-84970] - Staining in human ovary and cerebral cortex tissues using anti-DCN antibody. Corresponding DCN RNA-seq data are presented for the same tissues.