AMM03897G

antibody from Leading Biology

Targeting: PCMT1

Western blot (Recommended by provider)

Antibody Data

Product number

AMM03897G

Provider

Leading Biology

Product name

PCMT1 Antibody (monoclonal) (M01)

Antibody type

Monoclonal

Description

Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.

Reactivity

Human, Rat

Host

Mouse

Isotype

IgG

Antibody clone number

4G9

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.