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- Antigen structure
- References [119]
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- Product number
- 66184-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- P62,SQSTM1 antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated P62,SQSTM1 antibody (Cat. #66184-1-Ig) is a mouse monoclonal antibody that shows reactivity with human and has been validated for the following applications: FC, IF, IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1H5C1
- Vial size
- 20ul, 150ul
Submitted references Gut bacteria-driven homovanillic acid alleviates depression by modulating synaptic integrity.
N-acetylneuraminic acid modulates SQSTM1/p62 sialyation-mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice.
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Deficiency of purinergic P2X4 receptor alleviates experimental autoimmune hepatitis in mice.
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Downregulation of SMAD4 protects HaCaT cells against UVB-induced damage and oxidative stress through the activation of EMT.
Huanglian Jiedu decoction inhibits vascular smooth muscle cell-derived foam cell formation by activating autophagy via suppressing P2RY12.
CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
Supramolecular Nanofibers Ameliorate Bleomycin-Induced Pulmonary Fibrosis by Restoring Autophagy.
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing.
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction.
Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway.
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Hepatoprotective effect of dietary pterostilbene against high-fat-diet-induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation.
Mechanistic insights into Qiteng Xiaozhuo Granules' regulation of autophagy for chronic glomerulonephritis treatment: Serum pharmacochemistry, network pharmacology, and experimental validation.
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
Mesenchymal stem cell-derived exosomes ameliorate TGF-β1-induced endometrial fibrosis by altering their miRNA profile.
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation.
A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy.
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β.
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator.
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Low Pi stress enhances the sensitivity of hepatocellular carcinoma to sorafenib.
Selenium Nanodots (SENDs) as Antioxidants and Antioxidant-Prodrugs to Rescue Islet β Cells in Type 2 Diabetes Mellitus by Restoring Mitophagy and Alleviating Endoplasmic Reticulum Stress.
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer.
Hyperlipidemia impacts osteogenesis via lipophagy.
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.
Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome.
A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Zinc Oxide Nanoparticle Improves the Intestinal Function of Intrauterine Growth Retardation Finishing Pigs via Regulating Intestinal Morphology, Inflammation, Antioxidant Status and Autophagy.
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Artemisinin Alleviates Cerebral Ischemia/Reperfusion-Induced Oxidative Damage via Regulating PHB2-Mediated Autophagy in the Human Neuroblastoma SH-SY5Y Cell Line.
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Yifei sanjie Pills Alleviate Chemotherapy-Related Fatigue by Reducing Skeletal Muscle Injury and Inhibiting Tumor Growth in Lung Cancer Mice.
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway.
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Protocatechualdehyde Rescues Oxygen-Glucose Deprivation/Reoxygenation-Induced Endothelial Cells Injury by Inducing Autophagy and Inhibiting Apoptosis via Regulation of SIRT1.
Long non-coding RNA IGFBP7-AS1 promotes odontogenic differentiation of stem cells from human exfoliated deciduous teeth through autophagy: An in vitro study.
Moxidectin induces autophagy arrest in colorectal cancer.
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Lipopolysaccharide reduces melanin synthesis in vitiligo melanocytes by regulating autophagy.
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells.
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5.
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer.
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling.
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency.
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Autophagy and apoptosis mediated nano-copper-induced testicular damage.
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Protectin DX Attenuates Lumbar Radicular Pain of Non-compressive Disc Herniation by Autophagy Flux Stimulation via Adenosine Monophosphate-Activated Protein Kinase Signaling.
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment.
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Pathogenic mechanism of congenital cataract caused by the CRYBA1/A3-G91del variant and related intervention strategies.
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Bidirectional role of reactive oxygen species during inflammasome activation in acrolein-induced human EAhy926 cells pyroptosis.
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways.
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells.
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
In vivo and in vitro studies using Clonorchis sinensis adult-derived total protein (CsTP) on cellular function and inflammatory effect in mouse and cell model.
Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway.
Phenotypic Drug Screening for Dysferlinopathy Using Patient-Derived Induced Pluripotent Stem Cells.
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Sirtuin6 (SIRT6) Promotes the EMT of Hepatocellular Carcinoma by Stimulating Autophagic Degradation of E-Cadherin.
Parkin truncating variants result in a loss-of-function phenotype.
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
Clinicopathological description of two cases with SQSTM1 gene mutation associated with frontotemporal dementia.
Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.
Zhao M, Ren Z, Zhao A, Tang Y, Kuang J, Li M, Chen T, Wang S, Wang J, Zhang H, Wang J, Zhang T, Zeng J, Liu X, Xie G, Liu P, Sun N, Bao T, Nie T, Lin J, Liu P, Zheng Y, Zheng X, Liu T, Jia W
Cell metabolism 2024 May 7;36(5):1000-1012.e6
Cell metabolism 2024 May 7;36(5):1000-1012.e6
N-acetylneuraminic acid modulates SQSTM1/p62 sialyation-mediated ubiquitination degradation contributing to vascular endothelium dysfunction in experimental atherosclerosis mice.
Chen L, Qiu H, Chen Q, Xiang P, Lei J, Zhang J, Lu Y, Wang X, Wu S, Yu C, Ma L
IUBMB life 2024 Mar;76(3):161-178
IUBMB life 2024 Mar;76(3):161-178
NDRG1 overcomes resistance to immunotherapy of pancreatic ductal adenocarcinoma through inhibiting ATG9A-dependent degradation of MHC-1.
Zhang Z, Song B, Wei H, Liu Y, Zhang W, Yang Y, Sun B
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2024 Mar;73:101040
Deficiency of purinergic P2X4 receptor alleviates experimental autoimmune hepatitis in mice.
Liu Z, Sun M, Liu W, Feng F, Li X, Jin C, Zhang Y, Wang J
Biochemical pharmacology 2024 Mar;221:116033
Biochemical pharmacology 2024 Mar;221:116033
Proteomic Characterization Identifies Clinically Relevant Subgroups of Gastrointestinal Stromal Tumors.
Sun M, Tong Y, Yuan W, Wang Y, Pu Y, Huang W, Lv B, Xu C, Jiang W, Luo R, Fang R, Tang S, Ren L, Wang J, Feng J, Sun C, Shen K, He F, Hou Y, Ding C
Gastroenterology 2024 Mar;166(3):450-465.e33
Gastroenterology 2024 Mar;166(3):450-465.e33
IGF2BP3 prevent HMGB1 mRNA decay in bladder cancer and development.
Lv L, Wei Q, Zhang J, Dong Y, Shan Z, Chang N, Zhao Y, Bian P, Yi Q
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Cellular & molecular biology letters 2024 Mar 19;29(1):39
Downregulation of SMAD4 protects HaCaT cells against UVB-induced damage and oxidative stress through the activation of EMT.
Li X, Wang Y, Wang X, Shen Y, Yuan Y, He Q, Mao S, Wu C, Zhou M
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Jun;23(6):1051-1065
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 2024 Jun;23(6):1051-1065
Huanglian Jiedu decoction inhibits vascular smooth muscle cell-derived foam cell formation by activating autophagy via suppressing P2RY12.
Lin J, Gu M, Wang X, Chen Y, Chau NV, Li J, Chu Q, Qing L, Wu W
Journal of ethnopharmacology 2024 Jun 28;328:118125
Journal of ethnopharmacology 2024 Jun 28;328:118125
CDK5RAP3 is a novel super-enhancer-driven gene activated by master TFs and regulates ER-Phagy in neuroblastoma.
Zhuo R, Zhang Z, Chen Y, Li G, Du S, Guo X, Yang R, Tao Y, Li X, Fang F, Xie Y, Wu D, Yang Y, Yang C, Yin H, Qian G, Wang H, Yu J, Jia S, Zhu F, Feng C, Wang J, Xu Y, Li Z, Shi L, Wang X, Pan J, Wang J
Cancer letters 2024 Jun 1;591:216882
Cancer letters 2024 Jun 1;591:216882
Supramolecular Nanofibers Ameliorate Bleomycin-Induced Pulmonary Fibrosis by Restoring Autophagy.
Zheng D, Guo J, Liang Z, Jin Y, Ding Y, Liu J, Qi C, Shi K, Xie L, Zhu M, Wang L, Hu Z, Yang Z, Liu Q, Li X, Ning W, Gao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2401327
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Jul;11(28):e2401327
Role of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in autophagy activation following subarachnoid hemorrhage.
Huo J, Dong W, Xu J, Ma L, You C
Experimental neurology 2024 Jan;371:114577
Experimental neurology 2024 Jan;371:114577
Revealing the mechanism of 755-nm long-pulsed alexandrite laser in inhibiting infantile hemangioma endothelial cells through transcriptome sequencing.
Ke C, Chen C, Yang M, Chen H, Li L, Ke Y
Lasers in medical science 2024 Jan 18;39(1):37
Lasers in medical science 2024 Jan 18;39(1):37
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction.
Ryu S, Long H, Zheng XL, Song YY, Wang Y, Zhou YJ, Quan XJ, Li LY, Zhang ZS
Acta pharmacologica Sinica 2024 Feb;45(2):378-390
Acta pharmacologica Sinica 2024 Feb;45(2):378-390
Thioredoxin-1 decreases alpha-synuclein induced by MPTP through promoting autophagy-lysosome pathway.
Gu R, Bai L, Yan F, Zhang S, Zhang X, Deng R, Zeng X, Sun B, Hu X, Li Y, Bai J
Cell death discovery 2024 Feb 22;10(1):93
Cell death discovery 2024 Feb 22;10(1):93
Teadenol B as a Component of Microorganism-Fermented Tea Extract Inhibited Breast Cancers by Promoting Autophagy.
Zhao Y, Ding ZG, Yan YJ, Yang R, Qi MM, Pan SK, Xie JL, Sun YH, Xiang J
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Molecules (Basel, Switzerland) 2024 Feb 16;29(4)
Hepatoprotective effect of dietary pterostilbene against high-fat-diet-induced lipid accumulation exacerbated by chronic jet lag via SIRT1 and SIRT3 activation.
Koh YC, Yao CH, Lee PS, Nagabhushanam K, Ho CT, Pan MH
Phytotherapy research : PTR 2024 Aug;38(8):4099-4113
Phytotherapy research : PTR 2024 Aug;38(8):4099-4113
Mechanistic insights into Qiteng Xiaozhuo Granules' regulation of autophagy for chronic glomerulonephritis treatment: Serum pharmacochemistry, network pharmacology, and experimental validation.
Liu T, Zhuang XX, Tang YY, Gao YC, Gao JR
Journal of ethnopharmacology 2024 Apr 24;324:117819
Journal of ethnopharmacology 2024 Apr 24;324:117819
Transcutaneous Electrical Nerve Stimulation (TENS) Alleviates Brain Ischemic Injury by Regulating Neuronal Oxidative Stress, Pyroptosis, and Mitophagy.
Tan Z, Dong F, Wu L, Feng Y, Zhang M, Zhang F
Mediators of inflammation 2023;2023:5677865
Mediators of inflammation 2023;2023:5677865
Mesenchymal stem cell-derived exosomes ameliorate TGF-β1-induced endometrial fibrosis by altering their miRNA profile.
Zhou L, Dong L, Li H, Liu H, Yang J, Huang Z
American journal of translational research 2023;15(5):3203-3216
American journal of translational research 2023;15(5):3203-3216
Antisense lncRNA-RP11-498C9.13 promotes bladder cancer progression by enhancing reactive oxygen species-induced mitophagy.
Song W, Li Z, Yang K, Gao Z, Zhou Q, Li P
The journal of gene medicine 2023 Sep;25(9):e3527
The journal of gene medicine 2023 Sep;25(9):e3527
1,8-Cineole ameliorates endothelial injury and hypertension induced by L-NAME through regulation of autophagy via PI3K/mTOR signaling pathway.
Chen M, Hu Q, Wang S, Tao L, Hu X, Shen X
European journal of pharmacology 2023 Sep 5;954:175863
European journal of pharmacology 2023 Sep 5;954:175863
Cytotoxic immune cells do not affect TDP-43 and p62 sarcoplasmic aggregation but influence TDP-43 localisation.
McCord B, Day RM
Scientific reports 2023 Sep 23;13(1):15935
Scientific reports 2023 Sep 23;13(1):15935
A fluorene derivative inhibits human hepatocellular carcinoma cells by ROS-mediated apoptosis, anoikis and autophagy.
Urade R, Chang WT, Ko CC, Li RN, Yang HM, Chen HY, Huang LY, Chang MY, Wu CY, Chiu CC
Life sciences 2023 Sep 15;329:121835
Life sciences 2023 Sep 15;329:121835
DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells.
Lin J, Zheng X, Xiong Z, Xiang Q, Zhao Y, Jiang S, Sun Z, Fan D, Sun C, Li W
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1357-1371
Enhanced Mitophagy in Cholesteatoma Epithelial Cells.
Li QC, Wang SQ, Cao ZZ, Zhou SH
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology 2023 Oct 1;44(9):e688-e694
Characterization of circRNAs in established osimertinib‑resistant non‑small cell lung cancer cell lines.
Chen X, Gu J, Huang J, Wen K, Zhang G, Chen Z, Wang Z
International journal of molecular medicine 2023 Nov;52(5)
International journal of molecular medicine 2023 Nov;52(5)
Microcolin H, a novel autophagy inducer, exerts potent antitumour activity by targeting PITPα/β.
Yang H, Zhang X, Wang C, Zhang H, Yi J, Wang K, Hou Y, Ji P, Jin X, Li C, Zhang M, Huang S, Jia H, Hu K, Mou L, Wang R
Signal transduction and targeted therapy 2023 Nov 15;8(1):428
Signal transduction and targeted therapy 2023 Nov 15;8(1):428
Curcumin protects against doxorubicin induced oxidative stress by regulating the Keap1-Nrf2-ARE and autophagy signaling pathways.
Liao D, Shangguan D, Wu Y, Chen Y, Liu N, Tang J, Yao D, Shi Y
Psychopharmacology 2023 May;240(5):1179-1190
Psychopharmacology 2023 May;240(5):1179-1190
Natural exosome-like nanoparticles derived from ancient medicinal insect Periplaneta americana L. as a novel diabetic wound healing accelerator.
Liao Q, Su L, Pang L, Li J, Li H, Li J, Liu Y, Zhang J
Journal of nanobiotechnology 2023 May 26;21(1):169
Journal of nanobiotechnology 2023 May 26;21(1):169
A regulatory circuit comprising the CBP and SIRT7 regulates FAM134B-mediated ER-phagy.
Wang X, Jiang X, Li B, Zheng J, Guo J, Gao L, Du M, Weng X, Li L, Chen S, Zhang J, Fang L, Liu T, Wang L, Liu W, Neculai D, Sun Q
The Journal of cell biology 2023 May 1;222(5)
The Journal of cell biology 2023 May 1;222(5)
hASCs-derived exosomal miR-155-5p targeting TGFβR2 promotes autophagy and reduces pyroptosis to alleviate intervertebral disc degeneration.
Chen D, Jiang X, Zou H
Journal of orthopaedic translation 2023 Mar;39:163-176
Journal of orthopaedic translation 2023 Mar;39:163-176
MicroRNA-183-5p regulates TAR DNA-binding protein 43 neurotoxicity via SQSTM1/p62 in amyotrophic lateral sclerosis.
Kim HC, Zhang Y, King PH, Lu L
Journal of neurochemistry 2023 Mar;164(5):643-657
Journal of neurochemistry 2023 Mar;164(5):643-657
A Novel Phenazine Analog, CPUL1, Suppresses Autophagic Flux and Proliferation in Hepatocellular Carcinoma: Insight from Integrated Transcriptomic and Metabolomic Analysis.
Chen J, Feng D, Lu Y, Zhang Y, Jiang H, Yuan M, Xu Y, Zou J, Zhu Y, Zhang J, Ge C, Wang Y
Cancers 2023 Mar 5;15(5)
Cancers 2023 Mar 5;15(5)
Low Pi stress enhances the sensitivity of hepatocellular carcinoma to sorafenib.
Bi QC, Deng ZQ, Lv YF, Liu Y, Xie CS, He YQ, Tang Q
Biochemical pharmacology 2023 Jul;213:115593
Biochemical pharmacology 2023 Jul;213:115593
Selenium Nanodots (SENDs) as Antioxidants and Antioxidant-Prodrugs to Rescue Islet β Cells in Type 2 Diabetes Mellitus by Restoring Mitophagy and Alleviating Endoplasmic Reticulum Stress.
Huang Q, Liu Z, Yang Y, Yang Y, Huang T, Hong Y, Zhang J, Chen Q, Zhao T, Xiao Z, Gong X, Jiang Y, Peng J, Nan Y, Ai K
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2300880
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jul;10(19):e2300880
MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer.
Shi X, Zou J, Wang Y, Zhao J, Ye B, Qi Q, Liu F, Hu J, Li S, Tian Y
IUBMB life 2023 Feb;75(2):117-136
IUBMB life 2023 Feb;75(2):117-136
Hyperlipidemia impacts osteogenesis via lipophagy.
Ji C, Zhang Z, Xu X, Song D, Zhang D
Bone 2023 Feb;167:116643
Bone 2023 Feb;167:116643
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation.
Xu Y, Wang Y, Xiao H, Li Y
Journal of periodontal research 2023 Dec;58(6):1248-1260
Journal of periodontal research 2023 Dec;58(6):1248-1260
E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC.
Tang F, Lu C, He X, Lin W, Xie B, Gao X, Peng Y, Yang D, Sun L, Weng L
Cell reports 2023 Dec 26;42(12):113477
Cell reports 2023 Dec 26;42(12):113477
Melatonin protects against developmental PBDE-47 neurotoxicity by targeting the AMPK/mitophagy axis.
Dong L, Sun Q, Qiu H, Yang K, Xiao B, Xia T, Wang A, Gao H, Zhang S
Journal of pineal research 2023 Aug;75(1):e12871
Journal of pineal research 2023 Aug;75(1):e12871
Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome.
Ge J, Wang Y, Chen X, Yu K, Luo ZQ, Liu X, Qiu J
Cell reports 2023 Aug 29;42(8):112817
Cell reports 2023 Aug 29;42(8):112817
A novel quinoline derivative, DFIQ, sensitizes NSCLC cells to ferroptosis by promoting oxidative stress accompanied by autophagic dysfunction and mitochondrial damage.
Bow YD, Ko CC, Chang WT, Chou SY, Hung CT, Huang JL, Tseng CH, Chen YL, Li RN, Chiu CC
Cancer cell international 2023 Aug 16;23(1):171
Cancer cell international 2023 Aug 16;23(1):171
Zinc Oxide Nanoparticle Improves the Intestinal Function of Intrauterine Growth Retardation Finishing Pigs via Regulating Intestinal Morphology, Inflammation, Antioxidant Status and Autophagy.
Zhou B, Zhang J, Liu H, Chen S, Wang T, Wang C
Frontiers in veterinary science 2022;9:884945
Frontiers in veterinary science 2022;9:884945
SS31 Ameliorates Oxidative Stress via the Restoration of Autophagic Flux to Protect Aged Mice From Hind Limb Ischemia.
Yang Q, Li C, Chen Q
Frontiers in cardiovascular medicine 2022;9:789331
Frontiers in cardiovascular medicine 2022;9:789331
Artemisinin Alleviates Cerebral Ischemia/Reperfusion-Induced Oxidative Damage via Regulating PHB2-Mediated Autophagy in the Human Neuroblastoma SH-SY5Y Cell Line.
Jiang M, Lai X, Zhang Y, Shen M, Ma H, Liu A, Wu J, Yan J
Oxidative medicine and cellular longevity 2022;2022:6568748
Oxidative medicine and cellular longevity 2022;2022:6568748
Ginsenoside Rh4 Inhibits Colorectal Cancer Cell Proliferation by Inducing Ferroptosis via Autophagy Activation.
Wu Y, Pi D, Chen Y, Zuo Q, Zhou S, Ouyang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Evidence-based complementary and alternative medicine : eCAM 2022;2022:6177553
Xuesaitong Combined with Dexmedetomidine Improves Cerebral Ischemia-Reperfusion Injury in Rats by Activating Keap1/Nrf2 Signaling and Mitophagy in Hippocampal Tissue.
Han GJ, Min XZ, Ma SS, Ding C, Wang XQ
Oxidative medicine and cellular longevity 2022;2022:5126042
Oxidative medicine and cellular longevity 2022;2022:5126042
Yifei sanjie Pills Alleviate Chemotherapy-Related Fatigue by Reducing Skeletal Muscle Injury and Inhibiting Tumor Growth in Lung Cancer Mice.
Wu Y, Pi D, Chen Y, Zuo Q, Lin L, Ouyang M
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2357616
Evidence-based complementary and alternative medicine : eCAM 2022;2022:2357616
Hugan Buzure Induces Autophagy and Apoptosis in Hepatocellular Carcinoma by Inhibiting PI3K/Akt/mTOR Signaling Pathway.
Meng X, Li M, Qiao M, Li X, Yang J, Hu J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1618491
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H(2)O(2) Through Activation of Nrf2 Pathway.
Qi S, Zhang X, Fu Z, Pi A, Shi F, Fan Y, Zhang J, Xiao T, Shang D, Lin M, Gao N, Chang J, Gao Y
Frontiers in pharmacology 2022;13:943111
Frontiers in pharmacology 2022;13:943111
Autophagy Inhibition Enhances the Anti-Tumor Activity of Methylseleninic Acid in Cisplatin-Resistance Human Lung Adenocarcinoma Cells.
Xin M, Gao Q, Xiang X, Xu J, Jiao Y, Li X, Zhang X, Jia X
Frontiers in pharmacology 2022;13:890974
Frontiers in pharmacology 2022;13:890974
Protocatechualdehyde Rescues Oxygen-Glucose Deprivation/Reoxygenation-Induced Endothelial Cells Injury by Inducing Autophagy and Inhibiting Apoptosis via Regulation of SIRT1.
Cao S, Chen S, Qiao X, Guo Y, Liu F, Ding Z, Jin B
Frontiers in pharmacology 2022;13:846513
Frontiers in pharmacology 2022;13:846513
Long non-coding RNA IGFBP7-AS1 promotes odontogenic differentiation of stem cells from human exfoliated deciduous teeth through autophagy: An in vitro study.
Wang D, Zhu N, Xie F, Qin M, Wang Y
Archives of oral biology 2022 Sep;141:105492
Archives of oral biology 2022 Sep;141:105492
Moxidectin induces autophagy arrest in colorectal cancer.
Mao Y, Xie H, Shu D, Cheng L, Lan J, Pan K
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
Medical oncology (Northwood, London, England) 2022 Sep 29;39(12):211
MED16 Promotes Tumour Progression and Tamoxifen Sensitivity by Modulating Autophagy through the mTOR Signalling Pathway in ER-Positive Breast Cancer.
Li H, Li K, Shu D, Shen M, Tan Z, Zhang W, Pu D, Tan W, Tang Z, Jin A, Liu S
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Life (Basel, Switzerland) 2022 Sep 20;12(10)
Lipopolysaccharide reduces melanin synthesis in vitiligo melanocytes by regulating autophagy.
Sun L, Sun J, Huo X, Feng Q, Li Y, Xie X, Geng S
Experimental dermatology 2022 Oct;31(10):1579-1585
Experimental dermatology 2022 Oct;31(10):1579-1585
Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells.
Deng L, Zhao M, Cui Y, Xia Q, Jiang L, Yin H, Zhao L
Drug and chemical toxicology 2022 Nov;45(6):2601-2612
Drug and chemical toxicology 2022 Nov;45(6):2601-2612
Gaseous signal molecule SO(2) regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
Zhao J, Wu Q, Yang T, Nie L, Liu S, Zhou J, Chen J, Jiang Z, Xiao T, Yang J, Chu C
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 2022 Nov 1;26(6):541-556
TPI1 activates the PI3K/AKT/mTOR signaling pathway to induce breast cancer progression by stabilizing CDCA5.
Jin X, Wang D, Lei M, Guo Y, Cui Y, Chen F, Sun W, Chen X
Journal of translational medicine 2022 May 4;20(1):191
Journal of translational medicine 2022 May 4;20(1):191
Apigenin alleviated PA-induced pyroptosis by activating autophagy in hepatocytes.
Meng Z, Zhu B, Gao M, Wang G, Zhou H, Lu J, Guan S
Food & function 2022 May 23;13(10):5559-5570
Food & function 2022 May 23;13(10):5559-5570
Exosomes-derived miR-125-5p from cartilage endplate stem cells regulates autophagy and ECM metabolism in nucleus pulposus by targeting SUV38H1.
Chen D, Jiang X
Experimental cell research 2022 May 1;414(1):113066
Experimental cell research 2022 May 1;414(1):113066
SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells.
Zhao Y, Mao A, Zhang R, Guan S, Lu J
Environmental toxicology 2022 Mar;37(3):549-563
Environmental toxicology 2022 Mar;37(3):549-563
HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer.
Lei T, Huang J, Xie F, Gu J, Cheng Z, Wang Z
Acta biochimica et biophysica Sinica 2022 Mar 25;54(4):fpage-lpage
Acta biochimica et biophysica Sinica 2022 Mar 25;54(4):fpage-lpage
Overexpression of VPS16 correlates with tumor progression and chemoresistance in colorectal cancer.
Zhang B, Ma Y, Niu H, Liu Z
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Biochemical and biophysical research communications 2022 Jun 4;607:81-88
Oncostatin M receptor regulates osteoblast differentiation via extracellular signal-regulated kinase/autophagy signaling.
Zhou J, Yang J, Dong Y, Shi Y, Zhu E, Yuan H, Li X, Wang B
Stem cell research & therapy 2022 Jun 28;13(1):278
Stem cell research & therapy 2022 Jun 28;13(1):278
IL-27 regulates autophagy in rheumatoid arthritis fibroblast-like synoviocytes via STAT3 signaling.
Hou J, Gao W
Immunobiology 2022 Jul;227(4):152241
Immunobiology 2022 Jul;227(4):152241
Extracellular vesicle miR-32 derived from macrophage promotes arterial calcification in mice with type 2 diabetes via inhibiting VSMC autophagy.
Cao J, Chen C, Chen Q, Gao Y, Zhao Z, Yuan Q, Li A, Yang S, He Y, Zu X, Liu J
Journal of translational medicine 2022 Jul 6;20(1):307
Journal of translational medicine 2022 Jul 6;20(1):307
Resveratrol alleviates enterotoxigenic Escherichia coli K88-induced damage by regulating SIRT-1 signaling in intestinal porcine epithelial cells.
Luo X, Wu S, Jia H, Si X, Song Z, Zhai Z, Bai J, Li J, Yang Y, Wu Z
Food & function 2022 Jul 4;13(13):7346-7360
Food & function 2022 Jul 4;13(13):7346-7360
Magnetic hyperthermia induces effective and genuine immunogenic tumor cell death with respect to exogenous heating.
Yan B, Liu C, Wang S, Li H, Jiao J, Lee WSV, Zhang S, Hou Y, Hou Y, Ma X, Fan H, Lv Y, Liu X
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Journal of materials chemistry. B 2022 Jul 20;10(28):5364-5374
Inhibition of Nrf2 degradation alleviates age-related osteoporosis induced by 1,25-Dihydroxyvitamin D deficiency.
Yang R, Zhang J, Li J, Qin R, Chen J, Wang R, Goltzman D, Miao D
Free radical biology & medicine 2022 Jan;178:246-261
Free radical biology & medicine 2022 Jan;178:246-261
CHMP2B regulates TDP-43 phosphorylation and cytotoxicity independent of autophagy via CK1.
Deng X, Sun X, Yue W, Duan Y, Hu R, Zhang K, Ni J, Cui J, Wang Q, Chen Y, Li A, Fang Y
The Journal of cell biology 2022 Jan 3;221(1)
The Journal of cell biology 2022 Jan 3;221(1)
Autophagy and apoptosis mediated nano-copper-induced testicular damage.
Chen H, Wang Y, Luo J, Kang M, Hou J, Tang R, Zhao L, Shi F, Ye G, He X, Cui H, Guo H, Li Y, Tang H
Ecotoxicology and environmental safety 2022 Jan 1;229:113039
Ecotoxicology and environmental safety 2022 Jan 1;229:113039
Transcription factor EB enhances autophagy and ameliorates palmitate-induced insulin resistance at least partly via upregulating AMPK activity in skeletal muscle cells.
Wang P, Li CG, Zhou X, Ding S
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Clinical and experimental pharmacology & physiology 2022 Feb;49(2):302-310
Knocking Down Peroxiredoxin 6 Aggravates Cerebral Ischemia-Reperfusion Injury by Enhancing Mitophagy.
Hong T, Zhou Y, Peng L, Wu X, Li Y, Li Y, Zhao Y
Neuroscience 2022 Feb 1;482:30-42
Neuroscience 2022 Feb 1;482:30-42
Polyphyllin II induced apoptosis of NSCLC cells by inhibiting autophagy through the mTOR pathway.
Jiao Y, Xin M, Xu J, Xiang X, Li X, Jiang J, Jia X
Pharmaceutical biology 2022 Dec;60(1):1781-1789
Pharmaceutical biology 2022 Dec;60(1):1781-1789
GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Cell communication and signaling : CCS 2022 Aug 30;20(1):133
Inhibition of autophagy potentiates the cytotoxicity of the irreversible FGFR1-4 inhibitor FIIN-2 on lung adenocarcinoma.
Jia X, Xin M, Xu J, Xiang X, Li X, Jiao Y, Wang L, Jiang J, Pang F, Zhang X, Zhang J
Cell death & disease 2022 Aug 30;13(8):750
Cell death & disease 2022 Aug 30;13(8):750
Regulation of the sensitivity of hepatocarcinoma cells by ORMDL3, to sorafenib by autophagy.
Sun Y, Guan X, Zhang T, Li Y, Shi H, Chitakunye AT, Hong H, Zhang S, Zhu Q, Cai L
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):159
Medical oncology (Northwood, London, England) 2022 Aug 16;39(11):159
Downregulation of FAPP2 gene induces cell autophagy and inhibits PI3K/AKT/mTOR pathway in T-cell acute lymphoblastic leukemia.
Yuan T, Wang J, Shi C, Wang Y, Xia B, Xu W, Yang H, Yang Y, Ye MT, Khalid S, Liang Y, Tian C, You MJ, Wang Y
Hematological oncology 2022 Apr;40(2):249-257
Hematological oncology 2022 Apr;40(2):249-257
The alleviative effect of flavonol-type Nrf2 activator rhamnazin from Physalis alkekengi L. var. franchetii (Mast.) Makino on pulmonary disorders.
Wu XY, Wang T, Hu HX, Zhang K, Zhao Y, Zhao BB, Lou HX, Wang XN, Shen T
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
Phytotherapy research : PTR 2022 Apr;36(4):1692-1707
PPT1 Reduction Contributes to Erianin-Induced Growth Inhibition in Oral Squamous Carcinoma Cells.
Luo Q, Li X, Gan G, Yang M, Chen X, Chen F
Frontiers in cell and developmental biology 2021;9:764263
Frontiers in cell and developmental biology 2021;9:764263
GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy.
Guo W, Li W, Su Y, Liu S, Kan X, Ran X, Cao Y, Fu S, Liu J
International journal of biological sciences 2021;17(15):4271-4284
International journal of biological sciences 2021;17(15):4271-4284
Protectin DX Attenuates Lumbar Radicular Pain of Non-compressive Disc Herniation by Autophagy Flux Stimulation via Adenosine Monophosphate-Activated Protein Kinase Signaling.
Zhao QX, Wang YH, Wang SC, Xue S, Cao ZX, Sun T
Frontiers in physiology 2021;12:784653
Frontiers in physiology 2021;12:784653
Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk Protein.
Liu S, Guo W, Jia Y, Ye B, Liu S, Fu S, Liu J, Hu G
Frontiers in immunology 2021;12:782989
Frontiers in immunology 2021;12:782989
SARS-CoV-2 Causes Mitochondrial Dysfunction and Mitophagy Impairment.
Shang C, Liu Z, Zhu Y, Lu J, Ge C, Zhang C, Li N, Jin N, Li Y, Tian M, Li X
Frontiers in microbiology 2021;12:780768
Frontiers in microbiology 2021;12:780768
Selective STAT3 Inhibitor Alantolactone Ameliorates Osteoarthritis via Regulating Chondrocyte Autophagy and Cartilage Homeostasis.
Pei W, Huang X, Ni B, Zhang R, Niu G, You H
Frontiers in pharmacology 2021;12:730312
Frontiers in pharmacology 2021;12:730312
Collusion of α-Synuclein and Aβ aggravating co-morbidities in a novel prion-type mouse model.
Lloyd GM, Dhillon JS, Gorion KM, Riffe C, Fromholt SE, Xia Y, Giasson BI, Borchelt DR
Molecular neurodegeneration 2021 Sep 9;16(1):63
Molecular neurodegeneration 2021 Sep 9;16(1):63
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Inhibition of autophagy with Chloroquine enhanced apoptosis induced by 5-aminolevulinic acid-photodynamic therapy in secondary hyperparathyroidism primary cells and organoids.
Zeng L, Zou Q, Huang P, Xiong L, Cheng Y, Chen Q, Li Y, He H, Yi W, Wei W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 Oct;142:111994
Pathogenic mechanism of congenital cataract caused by the CRYBA1/A3-G91del variant and related intervention strategies.
Xu J, Wang H, Wu C, Wang A, Wu W, Xu J, Luo C, Ni S, Yao K, Chen X
International journal of biological macromolecules 2021 Oct 31;189:44-52
International journal of biological macromolecules 2021 Oct 31;189:44-52
UM-6 induces autophagy and apoptosis via the Hippo-YAP signaling pathway in cervical cancer.
Wang D, He J, Dong J, Wu S, Liu S, Zhu H, Xu T
Cancer letters 2021 Oct 28;519:2-19
Cancer letters 2021 Oct 28;519:2-19
Sanguinarine impairs lysosomal function and induces ROS-dependent mitophagy and apoptosis in human hepatocellular carcinoma cells.
Wang J, Su Q, Wu Q, Chen K, Ullah A, Ghauri MA, Zhang Y
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Archives of pharmacal research 2021 Nov;44(11):1025-1036
Bidirectional role of reactive oxygen species during inflammasome activation in acrolein-induced human EAhy926 cells pyroptosis.
Jiang L, Luo S, Qiu T, Li Q, Jiang C, Sun X, Yang G, Zhang C, Liu X, Jiang L
Toxicology mechanisms and methods 2021 Nov;31(9):680-689
Toxicology mechanisms and methods 2021 Nov;31(9):680-689
Cyanidin-3-O-glucoside and its metabolite protocatechuic acid ameliorate 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) induced cytotoxicity in HepG2 cells by regulating apoptotic and Nrf2/p62 pathways.
Zhao L, Zhou N, Zhang H, Pan F, Ai X, Wang Y, Hao S, Wang C
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112582
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Nov;157:112582
Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca(2+)/CaMKII signal pathway.
Chen TT, Zhou X, Xu YN, Li Y, Wu XY, Xiang Q, Fu LY, Hu XX, Tao L, Shen XC
Aging 2021 Mar 10;13(7):9542-9565
Aging 2021 Mar 10;13(7):9542-9565
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation.
Hu F, Song D, Yan Y, Huang C, Shen C, Lan J, Chen Y, Liu A, Wu Q, Sun L, Xu F, Hu F, Chen L, Luo X, Feng Y, Huang S, Hu J, Wang G
Nature communications 2021 Jun 15;12(1):3651
Nature communications 2021 Jun 15;12(1):3651
HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S
Oncology reports 2021 Jul;46(1)
Oncology reports 2021 Jul;46(1)
RabGEF1 functions as an oncogene in U251 glioblastoma cells and is involved in regulating AKT and Erk pathways.
Fan H, Xin T, Dong X, Yang F, Zhang R, Feng S, He D, Guo H, Pang Q
Experimental and molecular pathology 2021 Feb;118:104571
Experimental and molecular pathology 2021 Feb;118:104571
Oxidative stress-induced mitophagy is suppressed by the miR-106b-93-25 cluster in a protective manner.
Zhang C, Nie P, Zhou C, Hu Y, Duan S, Gu M, Jiang D, Wang Y, Deng Z, Chen J, Chen S, Wang L
Cell death & disease 2021 Feb 24;12(2):209
Cell death & disease 2021 Feb 24;12(2):209
Ginsenoside Rb1 alleviates liver injury induced by 3-chloro-1,2-propanediol by stimulating autophagic flux.
Lu J, Lu J, Bu X, Li Y, Ge G, Guan S
Journal of food science 2021 Dec;86(12):5503-5515
Journal of food science 2021 Dec;86(12):5503-5515
Upstream open reading frame with NOTCH2NLC GGC expansion generates polyglycine aggregates and disrupts nucleocytoplasmic transport: implications for polyglycine diseases.
Zhong S, Lian Y, Luo W, Luo R, Wu X, Ji J, Ji Y, Ding J, Wang X
Acta neuropathologica 2021 Dec;142(6):1003-1023
Acta neuropathologica 2021 Dec;142(6):1003-1023
Elevation of Hyaluronan Synthase by Magnesium Supplementation Mediated through the Activation of GSK3 and CREB in Human Keratinocyte-Derived HaCaT Cells.
Marunaka K, Shu S, Kobayashi M, Goto M, Katsuta Y, Yoshino Y, Ikari A
International journal of molecular sciences 2021 Dec 22;23(1)
International journal of molecular sciences 2021 Dec 22;23(1)
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner.
Deng Y, Chen QS, Huang WF, Dai JW, Wu ZJ
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Journal of gastrointestinal oncology 2021 Aug;12(4):1797-1810
Autocrined leptin promotes proliferation of non-small cell lung cancer (NSCLC) via PI3K/AKT and p53 pathways.
Wang J, Zhou F, Li F, Wang B, Hu Y, Li X
Annals of translational medicine 2021 Apr;9(7):568
Annals of translational medicine 2021 Apr;9(7):568
Reduction of Autophagosome Overload Attenuates Neuronal Cell Death After Traumatic Brain Injury.
Quan X, Song L, Zheng X, Liu S, Ding H, Li S, Xu G, Li X, Liu L
Neuroscience 2021 Apr 15;460:107-119
Neuroscience 2021 Apr 15;460:107-119
TAF1L promotes development of oral squamous cell carcinoma via decreasing autophagy-dependent apoptosis.
Wang D, Qi H, Zhang H, Zhou W, Li Y, Li A, Liu Q, Wang Y
International journal of biological sciences 2020;16(7):1180-1193
International journal of biological sciences 2020;16(7):1180-1193
Transcriptomic Analysis of Glycolysis-Related Genes Reveals an Independent Signature of Bladder Carcinoma.
Mou Z, Yang C, Zhang Z, Wu S, Xu C, Cheng Z, Dai X, Chen X, Ou Y, Jiang H
Frontiers in genetics 2020;11:566918
Frontiers in genetics 2020;11:566918
The c-Myc/miR-27b-3p/ATG10 regulatory axis regulates chemoresistance in colorectal cancer.
Sun W, Li J, Zhou L, Han J, Liu R, Zhang H, Ning T, Gao Z, Liu B, Chen X, Ba Y
Theranostics 2020;10(5):1981-1996
Theranostics 2020;10(5):1981-1996
In vivo and in vitro studies using Clonorchis sinensis adult-derived total protein (CsTP) on cellular function and inflammatory effect in mouse and cell model.
Shang M, Sun H, Wu Y, Gong Y, Tang Z, Meng F, He L, Yu X, Huang Y, Li X
Parasitology research 2020 May;119(5):1641-1652
Parasitology research 2020 May;119(5):1641-1652
Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway.
Guo W, Liu J, Li W, Ma H, Gong Q, Kan X, Cao Y, Wang J, Fu S
International journal of molecular sciences 2020 May 8;21(9)
International journal of molecular sciences 2020 May 8;21(9)
Phenotypic Drug Screening for Dysferlinopathy Using Patient-Derived Induced Pluripotent Stem Cells.
Kokubu Y, Nagino T, Sasa K, Oikawa T, Miyake K, Kume A, Fukuda M, Fuse H, Tozawa R, Sakurai H
Stem cells translational medicine 2019 Oct;8(10):1017-1029
Stem cells translational medicine 2019 Oct;8(10):1017-1029
Adiponectin inhibits high glucose-induced angiogenesis via inhibiting autophagy in RF/6A cells.
Li R, Du J, Yao Y, Yao G, Wang X
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Journal of cellular physiology 2019 Nov;234(11):20566-20576
Sirtuin6 (SIRT6) Promotes the EMT of Hepatocellular Carcinoma by Stimulating Autophagic Degradation of E-Cadherin.
Han LL, Jia L, Wu F, Huang C
Molecular cancer research : MCR 2019 Nov;17(11):2267-2280
Molecular cancer research : MCR 2019 Nov;17(11):2267-2280
Parkin truncating variants result in a loss-of-function phenotype.
Santos M, Morais S, Pereira C, Sequeiros J, Alonso I
Scientific reports 2019 Nov 6;9(1):16150
Scientific reports 2019 Nov 6;9(1):16150
hnRNPK modulates selective quality-control autophagy by downregulating the expression of HDAC6 in 293 cells.
Li Z, Liu X, Ma J, Zhang T, Gao X, Liu L
International journal of oncology 2018 Nov;53(5):2200-2212
International journal of oncology 2018 Nov;53(5):2200-2212
Rab11a is required for porcine reproductive and respiratory syndrome virus induced autophagy to promote viral replication.
Wang K, Li S, Worku T, Hao X, Yang L, Zhang S
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Biochemical and biophysical research communications 2017 Oct 14;492(2):236-242
Autophagy is essential for flavopiridol‑induced cytotoxicity against MCF‑7 breast cancer cells.
Wang S, Wang K, Wang H, Han J, Sun H
Molecular medicine reports 2017 Dec;16(6):9715-9720
Molecular medicine reports 2017 Dec;16(6):9715-9720
Clinicopathological description of two cases with SQSTM1 gene mutation associated with frontotemporal dementia.
Kovacs GG, van der Zee J, Hort J, Kristoferitsch W, Leitha T, Höftberger R, Ströbel T, Van Broeckhoven C, Matej R
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Feb;36(1):27-38
Neuropathology : official journal of the Japanese Society of Neuropathology 2016 Feb;36(1):27-38
Parkin-induced ubiquitination of Mff promotes its association with p62/SQSTM1 during mitochondrial depolarization.
Gao J, Qin S, Jiang C
Acta biochimica et biophysica Sinica 2015 Jul;47(7):522-9
Acta biochimica et biophysica Sinica 2015 Jul;47(7):522-9
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