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Cell line expression
Protein structure
SQSTM1
Sequestosome 1A170, OSIL, p60, p62, p62B, PDB3
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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| GeneTex |  GTX100685 |
25 references | Polyclonal |
WB
ICC
IP
IHC
FC
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| Proteintech Group | 18420-1-AP |
709 references | Polyclonal |
WB
EL
ICC
IP
IHC
FC
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| Novus Biologicals | H00008878-M01 |
236 references | Monoclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | MA5-27800 |
1 references | Monoclonal |
WB
ICC
IHC
FC
OA
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| antibodies-online | ABIN1449619 |
12 references | Polyclonal |
WB
EL
ICC
IHC
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