Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- H00000875-D01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00000875-D01P, RRID:AB_2290934
- Product name
- Rabbit Polyclonal CBS Antibody
- Antibody type
- Polyclonal
- Description
- Protein A purified. CBS - cystathionine-beta-synthase,
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Prenatal maternal stress induces visceral hypersensitivity of adult rat offspring through activation of cystathionine-β-synthase signaling in primary sensory neurons.
Coronary artery hypoxic vasorelaxation is augmented by perivascular adipose tissue through a mechanism involving hydrogen sulphide and cystathionine-β-synthase.
Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice.
The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model.
Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy.
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).
Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats.
Wang HJ, Xu X, Xie RH, Rui YY, Zhang PA, Zhu XJ, Xu GY
Molecular pain 2018 Jan-Dec;14:1744806918777406
Molecular pain 2018 Jan-Dec;14:1744806918777406
Coronary artery hypoxic vasorelaxation is augmented by perivascular adipose tissue through a mechanism involving hydrogen sulphide and cystathionine-β-synthase.
Donovan J, Wong PS, Garle MJ, Alexander SPH, Dunn WR, Ralevic V
Acta physiologica (Oxford, England) 2018 Dec;224(4):e13126
Acta physiologica (Oxford, England) 2018 Dec;224(4):e13126
Increased ophthalmic acid production is supported by amino acid catabolism under fasting conditions in mice.
Kobayashi S, Lee J, Takao T, Fujii J
Biochemical and biophysical research communications 2017 Sep 23;491(3):649-655
Biochemical and biophysical research communications 2017 Sep 23;491(3):649-655
The viability of primary hepatocytes is maintained under a low cysteine-glutathione redox state with a marked elevation in ophthalmic acid production.
Lee J, Kang ES, Kobayashi S, Homma T, Sato H, Seo HG, Fujii J
Experimental cell research 2017 Dec 1;361(1):178-191
Experimental cell research 2017 Dec 1;361(1):178-191
Hydrogen sulfide protects against the development of experimental cerebral malaria in a C57BL/6 mouse model.
Jiang P, Xu Z, Xiao B, Han Z, Huang J, Xu J, Lun Z, Zhou W
Molecular medicine reports 2017 Aug;16(2):2045-2050
Molecular medicine reports 2017 Aug;16(2):2045-2050
Ascorbic acid prevents acetaminophen-induced hepatotoxicity in mice by ameliorating glutathione recovery and autophagy.
Kurahashi T, Lee J, Nabeshima A, Homma T, Kang ES, Saito Y, Yamada S, Nakayama T, Yamada K, Miyata S, Fujii J
Archives of biochemistry and biophysics 2016 Aug 15;604:36-46
Archives of biochemistry and biophysics 2016 Aug 15;604:36-46
Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE).
Asimakopoulou A, Panopoulos P, Chasapis CT, Coletta C, Zhou Z, Cirino G, Giannis A, Szabo C, Spyroulias GA, Papapetropoulos A
British journal of pharmacology 2013 Jun;169(4):922-32
British journal of pharmacology 2013 Jun;169(4):922-32
Promoter demethylation of cystathionine-β-synthetase gene contributes to inflammatory pain in rats.
Qi F, Zhou Y, Xiao Y, Tao J, Gu J, Jiang X, Xu GY
Pain 2013 Jan;154(1):34-45
Pain 2013 Jan;154(1):34-45
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CBS Antibody [H00000875-D01P] - Analysis of CBS expression in transfected 293T cell line by CBS polyclonal antibody.Lane 1: CBS transfected lysate(60.60 KDa).Lane 2: Non-transfected lysate.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: CBS Antibody [H00000875-D01P] - Analysis of CBS expression in mouse kidney.