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Protein structure
CBS
Cystathionine beta-synthaseHIP4
The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2016]
Top validated antibodies |
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| Novus Biologicals |  H00000875-M01 |
48 references | Monoclonal |
WB
EL
ICC
IP
IHC
BN
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| Proteintech Group | 14787-1-AP |
103 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Abnova Corporation | H00000875-M01 |
32 references | Monoclonal |
WB
EL
IP
IHC
|
|
| Invitrogen Antibodies | PA5-22273 |
1 references | Polyclonal |
WB
ICC
IP
IHC
OA
|
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| antibodies-online | ABIN560206 |
38 references | Monoclonal |
WB
EL
IP
IHC
|
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