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- Antibody Data
- Antigen structure
- References [23]
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- Product number
- BAF401 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-1 beta/IL-1F2 Biotinylated Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects mouse IL-1 beta in ELISAs and Western blots. In sandwich immunoassays, less than 4% cross-reactivity with recombinant rat (rr) IL-1 beta is observed and less than 0.05% cross-reactivity with rhIL-1 beta and rmIL-1 alpha is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Biotin
- Antigen sequence
NP_032387- Isotype
- IgG
- Vial size
- 50 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice.
Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan.
The calcineurin-NFAT axis contributes to host defense during Pseudomonas aeruginosa lung infection.
Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-κB Activation.
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites.
Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice.
Glimepiride reduces CD14 expression and cytokine secretion from macrophages.
A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion.
Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway.
Regulator of calcineurin 1 suppresses inflammation during respiratory tract infections.
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
Response patterns of cytokines/chemokines in two murine strains after irradiation.
NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor.
Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
Sequential ELISA to profile multiple cytokines from small volumes.
Selective macrophage suppression during sepsis.
Kolb R, Kluz P, Tan ZW, Borcherding N, Bormann N, Vishwakarma A, Balcziak L, Zhu P, Davies BS, Gourronc F, Liu LZ, Ge X, Jiang BH, Gibson-Corley K, Klingelhutz A, Tan NS, Zhu Y, Sutterwala FS, Shen X, Zhang W
Oncogene 2019 Mar;38(13):2351-2363
Oncogene 2019 Mar;38(13):2351-2363
A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.
Polykratis A, Martens A, Eren RO, Shirasaki Y, Yamagishi M, Yamaguchi Y, Uemura S, Miura M, Holzmann B, Kollias G, Armaka M, van Loo G, Pasparakis M
Nature cell biology 2019 Jun;21(6):731-742
Nature cell biology 2019 Jun;21(6):731-742
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M
Nature 2018 Aug;560(7717):198-203
Nature 2018 Aug;560(7717):198-203
Anti-inflammatory Effects of the Natural Compounds Cortex Phellodendri and Humulus japonicus on Pelvic Inflammatory Disease in Mice.
Oh Y, Kwon YS, Jung BD
International journal of medical sciences 2017;14(8):729-734
International journal of medical sciences 2017;14(8):729-734
Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan.
Nam SY, Kim KY, Kim MH, Jang JB, Rah SY, Chae HJ, Lee JM, Kim HM, Jeong HJ
Pharmaceutical biology 2017 Dec;55(1):1856-1862
Pharmaceutical biology 2017 Dec;55(1):1856-1862
The calcineurin-NFAT axis contributes to host defense during Pseudomonas aeruginosa lung infection.
Pang Z, Junkins RD, MacNeil AJ, McCormick C, Cheng Z, Chen WM, Lin TJ
Journal of leukocyte biology 2017 Dec;102(6):1461-1469
Journal of leukocyte biology 2017 Dec;102(6):1461-1469
Oryza sativa (Rice) Hull Extract Inhibits Lipopolysaccharide-Induced Inflammatory Response in RAW264.7 Macrophages by Suppressing Extracellular Signal-regulated Kinase, c-Jun N-terminal Kinase, and Nuclear Factor-κB Activation.
Ha SK, Sung J, Choi I, Kim Y
Pharmacognosy magazine 2016 Oct-Dec;12(48):295-301
Pharmacognosy magazine 2016 Oct-Dec;12(48):295-301
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites.
Kim LK, Morita R, Kobayashi Y, Eisenbarth SC, Lee CG, Elias J, Eynon EE, Flavell RA
Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 2;112(22):E2891-9
Proceedings of the National Academy of Sciences of the United States of America 2015 Jun 2;112(22):E2891-9
Myeloid cell TRAF3 regulates immune responses and inhibits inflammation and tumor development in mice.
Lalani AI, Moore CR, Luo C, Kreider BZ, Liu Y, Morse HC 3rd, Xie P
Journal of immunology (Baltimore, Md. : 1950) 2015 Jan 1;194(1):334-48
Journal of immunology (Baltimore, Md. : 1950) 2015 Jan 1;194(1):334-48
Glimepiride reduces CD14 expression and cytokine secretion from macrophages.
Ingham V, Williams A, Bate C
Journal of neuroinflammation 2014 Jun 21;11:115
Journal of neuroinflammation 2014 Jun 21;11:115
A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion.
Bakker PJ, Butter LM, Claessen N, Teske GJ, Sutterwala FS, Florquin S, Leemans JC
The American journal of pathology 2014 Jul;184(7):2013-22
The American journal of pathology 2014 Jul;184(7):2013-22
Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway.
Ouyang X, Ghani A, Malik A, Wilder T, Colegio OR, Flavell RA, Cronstein BN, Mehal WZ
Nature communications 2013;4:2909
Nature communications 2013;4:2909
Regulator of calcineurin 1 suppresses inflammation during respiratory tract infections.
Junkins RD, MacNeil AJ, Wu Z, McCormick C, Lin TJ
Journal of immunology (Baltimore, Md. : 1950) 2013 May 15;190(10):5178-86
Journal of immunology (Baltimore, Md. : 1950) 2013 May 15;190(10):5178-86
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
Hara H, Tsuchiya K, Kawamura I, Fang R, Hernandez-Cuellar E, Shen Y, Mizuguchi J, Schweighoffer E, Tybulewicz V, Mitsuyama M
Nature immunology 2013 Dec;14(12):1247-55
Nature immunology 2013 Dec;14(12):1247-55
Response patterns of cytokines/chemokines in two murine strains after irradiation.
Zhang M, Yin L, Zhang K, Sun W, Yang S, Zhang B, Salzman P, Wang W, Liu C, Vidyasagar S, Zhang L, Ju S, Okunieff P, Zhang L
Cytokine 2012 May;58(2):169-77
Cytokine 2012 May;58(2):169-77
NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells.
Eisenbarth SC, Williams A, Colegio OR, Meng H, Strowig T, Rongvaux A, Henao-Mejia J, Thaiss CA, Joly S, Gonzalez DG, Xu L, Zenewicz LA, Haberman AM, Elinav E, Kleinstein SH, Sutterwala FS, Flavell RA
Nature 2012 Apr 25;484(7395):510-3
Nature 2012 Apr 25;484(7395):510-3
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
Wu W, Mehta H, Chakrabarty K, Booth JL, Duggan ES, Patel KB, Ballard JD, Coggeshall KM, Metcalf JP
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
TNF-alpha and IL-1beta mediate inflammatory hypernociception in mice triggered by B1 but not B2 kinin receptor.
Cunha TM, Verri WA Jr, Fukada SY, Guerrero AT, Santodomingo-Garzón T, Poole S, Parada CA, Ferreira SH, Cunha FQ
European journal of pharmacology 2007 Nov 14;573(1-3):221-9
European journal of pharmacology 2007 Nov 14;573(1-3):221-9
Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006 Nov;55(11):457-64
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2006 Nov;55(11):457-64
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
Osuchowski MF, Welch K, Siddiqui J, Remick DG
Journal of immunology (Baltimore, Md. : 1950) 2006 Aug 1;177(3):1967-74
Journal of immunology (Baltimore, Md. : 1950) 2006 Aug 1;177(3):1967-74
Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
Osuchowski MF, Welch K, Siddiqui J, Remick DG
Journal of immunology (Baltimore, Md. : 1950) 2006 Aug 1;177(3):1967-74
Journal of immunology (Baltimore, Md. : 1950) 2006 Aug 1;177(3):1967-74
Sequential ELISA to profile multiple cytokines from small volumes.
Osuchowski MF, Siddiqui J, Copeland S, Remick DG
Journal of immunological methods 2005 Jul;302(1-2):172-81
Journal of immunological methods 2005 Jul;302(1-2):172-81
Selective macrophage suppression during sepsis.
Ellaban E, Bolgos G, Remick D
Cellular immunology 2004 Sep-Oct;231(1-2):103-11
Cellular immunology 2004 Sep-Oct;231(1-2):103-11
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